Sarah Bonaparte

High sensitivity of the Bionote Anigen Rapid Rabies Antigen Test in detection of diverse rabies virus variants suggests utility for global rabies control

Lillian A. Orciari, Vaughn Wicker, Sarah Bonaparte, Pamela A. Yager et autres

ABSTRACT Point-of-care, immunochromatographic tests have not reliably detected the rabies virus and have not utilized a consistent diagnostic protocol. International diagnostic standards established by the World Organization for Animal Health require strategic and large-scale validation studies prior to widespread use. The United …

us, Ouganda, pr, Éthiopie, Zambie, au (code pays fourni par la source)

Chasing rabies herd immunity: evaluating dog vaccination strategies and post-vaccination survey reliability in urban and peri-urban Bangladesh

Catherine Swedberg, Umme Ruman Siddiqi, Ravikiran Keshavamurthy, Sohel Rana et autres

Introduction Mass dog vaccination (MDV) is essential for eliminating dog-mediated rabies, responsible for over 95% of the estimated 74,000 annual human rabies deaths. Achieving ≥ 70% vaccination coverage necessary for herd immunity remains challenging, underscoring the need for effective vaccination strategies and …

Ouganda, gb, bd, Tanzanie (code pays fourni par la source)

Human Rabies Deaths — Minnesota and California, 2024

Malia Ireland, Curtis L. Fritz, Stacy Holzbauer, Carrie Klumb et autres

Rabies is an enzootic viral disease in the continental United States and is typically transmitted through the bite of an infected mammal. Infection is almost always fatal if rabies postexposure prophylaxis (PEP) is not received before the onset of symptoms. Bats are …

us (code pays fourni par la source)

Human-to-Human Rabies Transmission via Solid Organ Transplantation from a Donor with Undiagnosed Rabies — United States, October 2024–February 2025

Rebecca Earnest, Kris K. Carter, Sara F. Margrey, Vaughn Wicker et autres

Although rabies virus is typically transmitted through mammalian animal bites or scratches, human-to-human transmission has occurred through organ and tissue transplantation. From 1978 to 2013, three transplant-transmitted rabies events in the United States affected nine tissue or organ recipients. Rabies is almost …

us (code pays fourni par la source)

Maximizing Human Rabies Case Detection: Understanding the Diagnostic Sensitivity of Antemortem Testing From 35 Years of US Data

Catherine Swedberg, Shama Cash‐Goldwasser, Yasmeen Ross, Shreya Mahadeven et autres

BACKGROUND: Human rabies underdetection is a global challenge due in part to under-testing. Antemortem diagnosis obviates challenges associated with postmortem testing and is critical to timely clinical and public health decision-making. This study aimed to characterize diagnostic sensitivity associated with specific antemortem …

us (code pays fourni par la source)

Wild and Domestic Animal Exposure among Deceased Persons Referred for Organ Procurement, United States

David W. McCormick, Raymond Lynch, Brianna Doby, Sarah B. Laskey et autres

Rabies is transmissible through transplantation. Wild mammal bites or scratches carry a high risk for rabies, but their frequency among organ donors is unknown. During 2024, an estimated 12 (95% CI 7-20; 0.07%) of 16,989 deceased US donors had high-risk exposures. Identifying …

Vaccination protects animal and human health and reduces the economic burden of preventable cases: rabies in vaccinated dogs and cats (2002–2022)

Cassandra Boutelle, Yasmeen Ross, Ryan M. Wallace, Sarah Bonaparte

Rabies vaccine failures in domestic animals can have severe public health consequences and are not consistently publicized. This study describes trends in rabies vaccine failures among dogs and cats in the US reported to the CDC's National Rabies Surveillance System between 2002 …

us (code pays fourni par la source)

Rabies surveillance in the United States during 2023

Cassandra Boutelle, Sarah Bonaparte, Lillian A. Orciari, Jordona D. Kirby et autres

Objective: Describe the epidemiologic landscape of rabies and rabies testing in the US during 2023 and provide an overview of rabies in Canada and Mexico. Methods: The US National Rabies Surveillance System collects monthly animal rabies testing data from 54 reporting jurisdictions. …

us, ca, ar (code pays fourni par la source)

Rabies vaccinations at the rural–urban divide: successes and barriers to dog rabies vaccination programs from a rural and urban campaign in Zambia

Ricky Chazya, Chilufya Mulenga, Andrew D. Gibson, Frederic Lohr et autres

Introduction Dog vaccination against rabies is considered one of the most effective strategies at preventing human deaths from rabies and is a key strategy for eliminating dog-mediated human rabies deaths. Traditional vaccination approaches in Zambia rarely collect operational data to assess coverage …

Zambie, us (code pays fourni par la source)

Rabies surveillance in the United States during 2022

Xiaoyue Ma, Cassandra Boutelle, Sarah Bonaparte, Lillian A. Orciari et autres

OBJECTIVE: To provide comprehensive epidemiological information about the distribution and occurrence of rabies during 2022 in the US, Canada, and Mexico. METHODS: The US National Rabies Surveillance System collected 2022 animal rabies data from US state and territorial public health departments and …

us, ca, mx (code pays fourni par la source)

Measuring the impact of an integrated bite case management program on the detection of canine rabies cases in Vietnam

Yasmeen Ross, Chuong Dinh Vo, Sarah Bonaparte, Minh Quang Phan et autres

Introduction: Dog-mediated rabies is enzootic in Vietnam, resulting in at least 70 reported human deaths and 500,000 human rabies exposures annually. In 2016, an integrated bite cases management (IBCM) based surveillance program was developed to improve knowledge of the dog-mediated rabies burden …

us, vn (code pays fourni par la source)

Evaluation of country infrastructure as an indirect measure of dog-mediated human rabies deaths

Sarah Bonaparte, Janae Moodie, Eduardo A. Undurraga, Ryan M. Wallace

Background: Rabies is a neglected disease, primarily due to poor detection stemming from limited surveillance and diagnostic capabilities in most countries. As a result, there is limited ability to monitor and evaluate country, regional, and global progress towards the WHO goal of …

us, cl (code pays fourni par la source)