Yves Blache

Potentiation of the antibiofilm effect of natural compound analogs in a marine bacterium by the cell permeabilization mechanism

Emmanuel Gozoua, Rose Koffi-Névry, Yves Blache

The potentiation of the anti-adhesion and anti-biofilm effects of the three compounds (OB1, AS194, AS162) was evaluated in this study. This potentiation is demonstrated by the combination of each of the three compounds with molecules of permeabilizing types which are Polymyxin B …

fr, Côte d’Ivoire (code pays fourni par la source)

The Marine Bacterium Shewanella woodyi Produces C8-HSL to Regulate Bioluminescence

Mahmoud Hayek, Claudine Baraquet, Raphaël Lami, Yves Blache et autres

fr (code pays fourni par la source)

Biofilm formation in marine bacteria and biocidal sensitivity: interplay between a potent antibiofilm compound (AS162) and quorum-sensing autoinducers

Emmanuel Gozoua, Rose Koffi-Névry, Yves Blache

fr, Côte d’Ivoire (code pays fourni par la source)

Current Trends in Disease and Health Vol. 1

Ronald Bartzatt, Innocent Emmanuel, Mansur Aliyu Ramalan, Adam Ochigbo et autres

Towards eco‐friendly biocides: preparation, antibiofilm activity of hemibastadin analogues

Alain Aka Kacou, Aimeric Ouvrard, Dominique Jamet, Jean‐Louis Jamet et autres

The antibiofilm activity of three hemibastadins analogues was evaluated against different marine bacterial strains through mono‐species biofilms and through a multi‐species model of biofilm. Results showed that compound 3 exhibited interesting antibiofilm efficiencies effective concentrations (EC50) in the range of 30–100 μmol …

fr (code pays fourni par la source)

Synthesis of Lamellarin Q Analogues as Potential Antibiofilm Compounds

Annie Praud‐Tabariès, Olivier Bottzeck, Yves Blache

An efficient synthesis of lamellarin Q analogues is described. This involves a two‐step procedure through a “Cu‐catalyzed” 1,3‐cycloaddtion and a “Pd‐catalyzed” arylation allowing high degrees of chemical diversity in view of structure–activity relationship studies in the field of antibiofilm activities.

fr (code pays fourni par la source)

Modular syntheses of 1,4,5-trisubstituted 1,2,3-triazoles by a one-pot three-step procedure: toward bio-inspired monomers

Annie Praud‐Tabariès, Olivier Bottzeck, Yves Blache

fr (code pays fourni par la source)

Parallel synthesis of a bis-triazoles library as psammaplin A analogues: A new wave of antibiofilm compounds?

Sofyane Andjouh, Yves Blache

fr (code pays fourni par la source)

Towards smart biocide-free anti-biofilm strategies: Click-based synthesis of cinnamide analogues as anti-biofilm compounds against marine bacteria

Cheikh Tidiane Sall, Mireille Ayé, Olivier Bottzeck, Annie Praud et autres

Sénégal, fr (code pays fourni par la source)

Influence of Substituents on the Antiplasmodial and Cytotoxic Activities of 5-chloro-3,4-dihydro-1H-pyrano[3,4-b]-1,10-phenanthrolinone as Antimalarial Agent

Cheikh Tidiane Sall, Samba Fama Ndoye, Matar Seck, Alexis Valentin et autres

International audience

Sénégal, fr (code pays fourni par la source)

Screening of bromotyramine analogues as antifouling compounds against marine bacteria

Sofyane Andjouh, Yves Blache

Rapid and efficient synthesis of 23 analogues inspired by bromotyramine derivatives, marine natural products, by means of CuSO4-catalysed [3+2] alkyne-azide cycloaddition is described. The final target was then assayed for anti-biofilm activity against three Gram-negative marine bacteria, Pseudoalteromonas ulvae (TC14), Pseudoalteromonas lipolytica …

fr (code pays fourni par la source)

Tropical microalgae isolated on Reunion island (France, Indian Ocean) as sources of antifouling molecules: The BIOPAINTROP project

Laurent Dufossé, Alexis Bazire, Yves Blache, Laurent Blériot et autres

re, fr (code pays fourni par la source)