Michelle de la Vega

Replication of De Neys, W., Rossi, S., & Houdé, O. (2013). at BYU-Idaho Winter 2018

Jannise Estrada, Merrydith Sheppard, Mykel Opheim, Bradford J. Wiggins et autres

Supplementary Figure 1 from The Deubiquitinating Enzyme USP17 Is Highly Expressed in Tumor Biopsies, Is Cell Cycle Regulated, and Is Required for G1-S Progression

Cheryl McFarlane, Alyson A. Kelvin, Michelle de la Vega, Ureshnie Govender et autres

Supplementary Figure 1 from The Deubiquitinating Enzyme USP17 Is Highly Expressed in Tumor Biopsies, Is Cell Cycle Regulated, and Is Required for G1-S Progression

Supplementary Figure 1 from The Deubiquitinating Enzyme USP17 Is Highly Expressed in Tumor Biopsies, Is Cell Cycle Regulated, and Is Required for G1-S Progression

Cheryl McFarlane, Alyson A. Kelvin, Michelle de la Vega, Ureshnie Govender et autres

Supplementary Figure 1 from The Deubiquitinating Enzyme USP17 Is Highly Expressed in Tumor Biopsies, Is Cell Cycle Regulated, and Is Required for G1-S Progression

Data from The Deubiquitinating Enzyme USP17 Is Highly Expressed in Tumor Biopsies, Is Cell Cycle Regulated, and Is Required for G1-S Progression

Cheryl McFarlane, Alyson A. Kelvin, Michelle de la Vega, Ureshnie Govender et autres

Abstract Ubiquitination is a reversible posttranslational modification that is essential for cell cycle control, and it is becoming increasingly clear that the removal of ubiquitin from proteins by deubiquitinating enzymes (DUB) is equally important. In this study, we have identified high levels …

Data from The Deubiquitinating Enzyme USP17 Is Highly Expressed in Tumor Biopsies, Is Cell Cycle Regulated, and Is Required for G1-S Progression

Cheryl McFarlane, Alyson A. Kelvin, Michelle de la Vega, Ureshnie Govender et autres

Abstract Ubiquitination is a reversible posttranslational modification that is essential for cell cycle control, and it is becoming increasingly clear that the removal of ubiquitin from proteins by deubiquitinating enzymes (DUB) is equally important. In this study, we have identified high levels …

Method and Materials

Jannise Estrada, Merrydith Sheppard, Mykel Opheim, Bradford J. Wiggins et autres

Data, Stats and Results Files

Rebecca Pearson, Michelle de la Vega, Merrydith Sheppard, Bradford J. Wiggins et autres

PTRH2 gene mutation causes progressive congenital skeletal muscle pathology

Jinger Doe, Angela M. Kaindl, Mayumi Jijiwa, Michelle de la Vega et autres

Peptidyl-tRNA hydrolase 2 (PTRH2) regulates integrin-mediated pro-survival and apoptotic signaling. PTRH2 is critical in muscle development and regulates myogenic differentiation. In humans a biallelic mutation in the PTRH2 gene causes infantile-onset multisystem disease with progressive muscle weakness. We report here that the …

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Bit1 is an essential regulator of myogenic differentiation

Genevieve S. Griffiths, Jinger Doe, Mayumi Jijiwa, Pam Van Ry et autres

Bit-1 is an essential regulator of myogenic differentiation

Genevieve S. Griffiths, Jinger Doe, Mayumi Jijiwa, Pam Van Ry et autres

Muscle differentiation requires a complex signaling cascade that leads to the production of multinucleated myofibers. Genes regulating the intrinsic mitochondrial apoptotic pathway also function in controlling cell differentiation. How such signaling pathways are regulated during differentiation is not fully understood. Bit-1 (also …

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Mutations in PTRH2 cause novel infantile‐onset multisystem disease with intellectual disability, microcephaly, progressive ataxia, and muscle weakness

Hao Hu, Michelle L. Matter, Lina Issa‐Jahns, Mayumi Jijiwa et autres

OBJECTIVE: To identify the cause of a so-far unreported phenotype of infantile-onset multisystem neurologic, endocrine, and pancreatic disease (IMNEPD). METHODS: We characterized a consanguineous family of Yazidian-Turkish descent with IMNEPD. The two affected children suffer from intellectual disability, postnatal microcephaly, growth retardation, …

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USP17 is required for clathrin mediated endocytosis of epidermal growth factor receptor

Jakub Jaworski, Michelle de la Vega, Sarah J. Fletcher, Cheryl McFarlane et autres

// Jakub Jaworski 1 , Michelle de la Vega 2 , Sarah J. Fletcher 3 , Cheryl McFarlane 2 , Michelle K. Greene 1 , Andrew W. Smyth 1 , Sandra Van Schaeybroeck 4 , James A. Johnston 2,5 , Christopher J. …

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