Harsh Raj Singh

Proniosome Gel for Chikungunya: Integrating Novel Drug Delivery with PBPK Modeling for Enhanced Therapeutic Outcomes

Dinesh Kumar, Gulshan Kumar, Harsh Raj Singh

Introduction: Chikungunya Virus (CHIKV), a mosquito-borne alphavirus, poses a persistent global health challenge due to the lack of effective antiviral therapies or vaccines. The infection manifests with acute fever and chronic arthralgia, often resulting in prolonged disability and economic burden. This study …

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Design and Development of Tribometers: A Comprehensive Review

Harsh Raj Singh, Pranav Jadhal, Vikas Kumar Singh

Frictional losses account for approximately 23% of global annual energy consumption, highlighting the importance of tribological research in improving mechanical efficiency and durability.Tribometry, as the experimental foundation of tribology, enables the measurement of friction coefficients, wear rates, and lubrication effectiveness under controlled …

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Nanochemistry Innovations: Revolutionizing Healthcare, Energy, and Environmental Sustainability

Dinesh Kumar, Harsh Raj Singh, Rajni Tanwar, Vrinda Gupta

Introduction: Nanochemistry, the convergence of chemistry and nanotechnology, has emerged as a transformative field addressing pressing global challenges in healthcare, energy, environment, agriculture, and industry. This review explores recent innovations, applications, and ethical considerations that define the current and future trajectory of …

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Innovations in Cancer Education: The Role of Emerging Leaders and Future Directions

Dinesh Kumar, Harsh Raj Singh, Nikita Verma, Vrinda Gupta et autres

Abstract: Cancer education is a very crucial aspect in equipping the medical personnel to meet the challenges of preventing, treating, and survivorship of cancer. This review addresses the program called the Emerging Leaders in Cancer Education, which targets building future leaders who …

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Duvyzat (Givinostat) in Duchenne Muscular Dystrophy: Mechanisms, Clinical Impact, and Future Directions

Dinesh Kumar, Rohan Kumar, Harsh Raj Singh, Rajni Tanwar

Duchenne Muscular Dystrophy (DMD) is a chronic, progressive neuromuscular disorder characterized by muscle degeneration and weakness due to mutations in the dystrophin gene. Although there is no cure, emerging therapies such as histone deacetylase (HDAC) inhibitors offer promising avenues to slow disease …

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Synthesis and Thermolysis of Possible Laser Material-Part I

Harsh Raj Singh, U. K. RATHI

Chemica laboratories, D. S. College, Aligarh-202 001 Manuscript received 24 September 1979, accepted 30 December 1979 Substituted ortho-hydroxy chalcones and acetophenone have been used as a co-ordinating ligand. The complex compounds of the ligands with Y(III), La(III). Pr(III) and Nd(lll) have been …

Thermolysis of Substituted Ortho-Hydroxy Acetophenone Oxime Complexes with Bivalent Metals-Part II

Harsh Raj Singh, U.K. RATHI, Priyanka Das, D. KUMAR

Chemical Laboratories, D. S. College, Aligarh-202 001 Department of Agricultural Chemistry, N. P. G. College, Shikohabad, India Manuscript received 24 September 1979, accepted 30 November 1979 Thermolysis of Substituted Ortho-Hydroxy Acetophenone Oxime Complexes with Bivalent Metals-Part II

Spectrophotometric Study of Uranium(VI) with 2-Hydroxy-5' -Halo Chalcone Chelate

Harsh Raj Singh, U.K. RATHI

Chemical Laboratories. D.S. College, Aligarh-201 001. India Manuscript received 25 September 1978, revised 21 August 1979, accepted 6 October 1979. Spectrophotometric Study of Uranium(VI) with 2-Hydroxy-5' -Halo Chalcone Chelate