Haifeng Lan

Agarotetrol alleviates reflux esophagitis by regulating autophagy through the METTL14/FOXO3a pathway

Xi Chen, Changyuan Yu, Xiangxiang Xu, Haifeng Lan et autres

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Clinical Study on the Application of Low-Dose 2L Lactulose Combined with Linaclotide in Bowel Preparation Before Colonoscopy

Haifeng Lan, Qiuyan Yang, Changqing Sun, Mei Shao et autres

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Intestinal Biofilms and Laxatives: Efficacy of Oral Sulfate Solution in Combination with Linaclotide for Pre-colonoscopy Bowel Preparation

Haifeng Lan, Shupei Li, Ya Yang, Qi Zhai et autres

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Erratum to: PHOSPHO1 Serves as a Key Metabolism-Related Biomarker in the Tumorigenesis of Diffuse Large B-cell Lymphoma

Tianrui Chen, Huang‐Ming Cao, Yin Wu, Jiang-tao Xie et autres

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PHOSPHO1 Serves as a Key Metabolism-Related Biomarker in the Tumorigenesis of Diffuse Large B-cell Lymphoma

Tianrui Chen, Huang-ming Cao, Yin Wu, Jiang-tao Xie et autres

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Identification of GLP1R and MCHR1 signaling as novel GPCR targets of MRAP2 protein

Meng Wang, Xu Jing, Xiaowei Lei, Cong Zhang et autres

The seven trans-membrane spanning G protein couple receptors(GPCRs) constitute the largest family of FDA approved drug targets to treat numerous human diseases, including metabolic associated disorders. The Melanocortin Receptor Accessory Protein 2 (MRAP2), a small single transmembrane protein broadly expressed in multiple …

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Abstract LB-379: Dominant negative PD1 armored CAR-T cells induce remission in relapsed or refractory non-Hodgkin lymphoma (NHL) patients

Yan Yuan, Liansheng Huang, Su Yang, Chengfei Pu et autres

Abstract The chimeric antigen receptor (CAR) T cell treatment has been demonstrated as an effective therapy to treat relapsed/refractory B cell malignancy. However, tumor microenvironment influences and affects the efficacy of CAR T treatment. For example, programmed death ligand 1/2 (PDL1/2) may …

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High Expression of the SH3TC2-DT/SH3TC2 Gene Pair Associated With FLT3 Mutation and Poor Survival in Acute Myeloid Leukemia: An Integrated TCGA Analysis

Pengfei Yu, Haifeng Lan, Xianmin Song, Zengkai Pan

Fms-like tyrosine kinase 3 (FLT3) mutation is one of the most common mutations in acute myeloid leukemia (AML). However, the effect of FLT3 mutation on survival is currently still controversial and the leukemogenic mechanisms are still under further investigation. The aim of …

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Dominant negative PD1 armored CART cells to induce remission in relapsed or refractory non-Hodgkin lymphoma (NHL) patients.

Chengfei Pu, Liansheng Huang, Yang Su, Tianling Ding et autres

e15028 Background: The chimeric antigen receptor (CAR) T cell treatment has been demonstrated as an effective therapy to treat relapsed/refractory B cell malignancy. However, tumor microenvironment influences and affects the efficacy of CAR T treatment. For example, programmed death ligand 1/2 (PDL1/2) …

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[The efficacy and safety analysis of bortezomib retreatment in 76 patients with relapsed/refractory multiple myeloma].

Jing Lü, Jian Hou, Chunyang Zhang, Zhen-Gang Yuan et autres

OBJECTIVE: To evaluate the efficacy and safety of bortezomib retreatment in 76 patients with relapsed/refractory multiple myeloma (MM), who previously responded to bortezomib. METHODS: Retrospective analysis of 76 MM patients, who had achieved at least a partial response (PR) on initial bortezomib …

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[Clinical observation of prophylactic lactulose for prevention of oral morphine-induced constipation].

Zhan Wang, Jianxin Qian, Xiao‐Dong Jiao, Lingyan Yuan et autres

OBJECTIVE: To evaluate the effects of different doses of lactulose on preventing oral morphine-induced constipation. METHODS: From January 2011 to May 2012, a total of 112 patients received oral lactulose solution to prevent morphine-induced constipation at our hospital and their clinical data …

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[Allogeneic peripheral blood stem cell transplantation from sibling donors for 10 patients with multiple myeloma].

Haifeng Lan, Zhengang Yuan, Chunyang Zhang, Yubao Chen et autres

OBJECTIVE: To evaluate the efficacy of allogeneic peripheral blood stem cell transplantation (allo-PBSCT) from sibling donors for treatment of multiple myeloma (MM). METHODS: Ten patients with MM received allo-PBSCT with conditioning consisting of fludarabine plus melphalan and cyclophosphamide mostly.CsA plus mycophenolate mofetil …

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