Karina Maia Paiva

Comparative analysis of cytoarchitectonic and neurochemical aspects of the globus pallidus in the rock cavy ( Kerodon rupestris ) and the common marmoset ( Callithrix jacchus )

Lavínnya Yáskara de Aquino Matoso, Yasmin Pinto Fernandes Albuquerque, Karina Maia Paiva, Rodrigo Freire Oliveira et autres

The globus pallidus (GP), a subcortical structure within the basal ganglia, plays a crucial role in modulating cortico-subcortical circuits related to motor control and associative/limbic functions. However, the cytoarchitectonic and neurochemical organization of this structure remains poorly characterized in naturally existing wild-type …

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Synaptic remodeling and the female depression exposome: a mini-review of neuroendocrine, epigenetic, and social determinants

Cindhi Mayra Rodrigues Xavier, Lucas Vinicius Faustino, Karina Maia Paiva, Rodrigo Freire Oliveira et autres

Depression is a multifactorial, chronic disorder and represents a leading cause of disability, with women exhibiting nearly twice the lifetime prevalence compared to men. Growing evidence indicates that this disparity cannot be explained by hormonal or psychosocial factors, but rather by dynamic …

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Analysis of NDNF and SLC1A2 gene expression in the dorsolateral prefrontal cortex of individuals with autism

Ariel Moraes de Andrade, Larysy Raquelly Vidal de Souza, Rodrigo Freire Oliveira, Karina Maia Paiva et autres

Introduction: This study investigated the expression of NDNF and SLC1A2 in the dorsolateral prefrontal cortex of individuals with Autism Spectrum Disorder (ASD), a region linked to executive functions, emotional regulation, social skills, and sensory processing. Methods: hybridization and Nissl staining. Histological images …

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Neurobiological basis of autism spectrum disorder: mini review

Maria Vanessa Freitas Holanda, Eva da Silva Paiva, Larissa Nayara de Souza, Karina Maia Paiva et autres

Autism Spectrum Disorder is a neuropsychiatric condition characterized by deficits in communication, social interaction, and repetitive behaviors, with significant symptom variability. This multifaceted profile reflects a complex genetic architecture as well as diversity in morphological characteristics. Therefore, the objective of this review …

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Flaxseed Oil Mitigates Stress-Induced Immunoreactivity Loss of Midbrain Tyrosine Hydroxylase-Positive neurons caused by High- intensity exercise training

Rodrigo F. Oliveira, Karina Maia Paiva, Antônio Vicente Dias de Andrade, Luenne Vitória Silva Oliveira Melo et autres

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O impacto do uso excessivo de telas no sono e neurodesenvolvimento infantil: uma revisão sistemática

Matheus de Medeiros Fernandes, Alexia Miranda Morais, Vitoria Cavalcante do Nascimento Frota, Gilliard do Nascimento et autres

Introdução: O sono é um dos principais mecanismos para o desenvolvimento neurológico, principalmenteno público infanto-juvenil. Entretanto, o aumento do uso de aparelhos eletrônicos por essa população gerou consequências no sono que necessitam de melhor avaliação. Objetivo: Avaliar, por meio de uma revisão …

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Calcium‐Binding Proteins in the Autistic Brain—Potential Links to Symptom Development

Élyssa Adriolly Freitas Tavares, Davi Dias Souza, Francisca Tayná da Silva Gomes, Maria Vanessa Freitas Holanda et autres

Autism spectrum disorder (ASD) is a complex challenge, influenced by genetic and environmental factors. This review focuses on the proteins calbindin (CB), calretinin (CR) and parvalbumin (PV) in the context of ASD, exploring their clinical correlations and providing a deeper understanding of …

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Correlação entre infecção crônica por Toxoplasma gondii e a prevalência de sintomas depressivos em humanos

Caio Felipe Rodrigues Barbosa, Alexsandro Teixeira de Morais, Fabiana Marques Ferreira Alves, Kaillanny Kettly Melo Freitas et autres

O Toxoplasma gondii (T. Gondii) é um parasita intracelular neuroinvasivo capaz de afetar o Sistema Nervoso Central. Embora a forma crônica da toxoplasmose seja frequentemente assintomática, estudos recentes sugerem que a presença do parasita pode causar alterações significativas nos neurotransmissores, resultando em …

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Volumetric alterations in the basal ganglia in autism Spectrum disorder: A systematic review

Gabriel Victor Teodoro de Medeiros Marcos, Deymisson Damitene Martins Feitosa, Karina Maia Paiva, Rodrigo F. Oliveira et autres

INTRODUCTION: Recent research indicates that some brain structures show alterations in conditions such as Autism Spectrum Disorder (ASD). Among them, are the basal ganglia that are involved in motor, cognitive and behavioral neural circuits. OBJECTIVE: Review the literature that describes possible volumetric …

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Physical exercise and flaxseed oil supplementation influence the glial plasticity in the rat hippocampus

Karina Maia Paiva, Rodrigo F. Oliveira, Lívia Helena Morais de Freitas, Acydália Madruga de Mendonça Florêncio de Melo et autres

Brain benefits from physical exercise associated with antioxidant supplements such as flaxseed oil. This low cost and simple association may improve hippocampal plasticity, which may work as a preventive and effective therapy in neuroprotection and neuroplasticity processes. This work evaluated the effects …

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Effect of senescence on the tyrosine hydroxylase and S100B immunoreactivity in the nigrostriatal pathway of the rat

Gabriel S. Rocha, Marco Aurélio M. Freire, Karina Maia Paiva, Rodrigo F. Oliveira et autres

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Allelopathy, toxicity and phytochemical profile of aqueous extracts from Aspidosperma pyrifolium and Combretum leprosum

José Carlos da Silveira Pereira, Karina Maia Paiva, Naama Jéssica de Assis Melo, Tallyson Nogueira Barbosa et autres

This study characterizes the allelopathic effect in the germination of Allium cepa seeds, and toxic on the species Artemia salina, of aqueous extracts of leaves of Aspidosperma pyrifolium and Combretum leprosum and the constituent phytochemical compositions. For this, Allium cepa seeds were …

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