Nils Krah

Five years of clinical application of independent Monte Carlo-based patient-specific quality assurance at Maastro Proton Therapy Center

Ilaria Rinaldi, Giorgio Cartechini, A. Schiavi, J. Gajewski et autres

INTRODUCTION: At the Maastro Proton Therapy Center in Maastricht, patient-specific quality assurance (PSQA) based on independent GPU-accelerated Monte Carlo (MC) dose calculations fully replaces conventional measurements. Measurement-based PSQA is time- and resource-intensive and has limited sensitivity to clinically relevant errors. We developed …

nl, it, pl (code pays fourni par la source)

THIN SEGMENTED SILICON SENSORS FOR CHARACTERIZING PROTON UHDR AND MINIBEAM DELIVERIES

Diango Montalvan Olivares, Umberto Deut, Arianna Ferro, Stefano De Astis et autres

Conclusions: Using direct proton WET measurements across diverse biological tissues, SECT calibration was shown to exhibit clinically relevant tissue-dependent bias, most notably in lung and bone, while DECT provided tissue-independent SPR estimation with markedly reduced WET deviations.These findings support DECT adoption for …

it, fr (code pays fourni par la source)

ABDOMINAL FLASH EFFECT: ULTRA HIGH DOSE RATE PROTON IRRADIATION IN A MURINE MODEL FOR GASTROESOPHAGEAL CANCER.

Andrea Vallés Martí, Anggraeini Puspitasari-Kokko, Nada Abdallah, Jeroen Essers et autres

nl (code pays fourni par la source)

MONTE CARLO VALIDATION AND UNCERTAINTY ANALYSIS OF UHDR COMPATIBLE 3D RANGE MODULATED BRAGG-PEAK PROTON THERAPY TREATMENT PLANS

Ylva Bornhauser, Anne Zur Horst, Nils Krah, Steven Habraken et autres

at emission stage and the profile of PG as detected by a knife-edge slit camera [8] were obtained with the built-in functions of the opensource MATLAB toolbox REGGUI.Results: 3D dose distributions were successfully reconstructed from simulated detected PG profile.The accuracy of the …

ch, nl (code pays fourni par la source)

BEAM COMMISSIONING AND EXPERIMENTAL VALIDATION OF A MC DOSE ENGINE FOR PLAN QA IN BRAGG-PEAK UHDR/FLASH PROTON THERAPY

Ylva Bornhauser, Anne Zur Horst, Thijs Van Staveren, Nils Krah et autres

Conclusions: Using direct proton WET measurements across diverse biological tissues, SECT calibration was shown to exhibit clinically relevant tissue-dependent bias, most notably in lung and bone, while DECT provided tissue-independent SPR estimation with markedly reduced WET deviations.These findings support DECT adoption for …

ch, nl (code pays fourni par la source)

FULLY AUTOMATED LOG-FILE-BASED PSQA PIPELINE IN PROTON THERAPY: FIVE YEARS OF CLINICAL EXPERIENCE

Ilaria Rinaldi, J. Gajewski, A. Schiavi, Nils Krah et autres

uz, pl, it, fr, nl (code pays fourni par la source)

GATE 10 Monte Carlo particle transport simulation: II. Architecture and innovations

Nils Krah, Nicolas Arbor, Thomas Baudier, Julien Bert et autres

Abstract Over the past years, we have developed GATE version 10, a major re-implementation of the long-standing Geant4-based Monte Carlo application for particle and radiation transport simulation in medical physics. This release introduces many new features and significant improvements, most notably a …

fr, cz, nl, at, be, gr, jp, de, pl, us, ca (code pays fourni par la source)

GATE 10 Monte Carlo particle transport simulation: I. Development and new features

David Sarrut, Nicolas Arbor, Thomas Baudier, Julien Bert et autres

We present GATE version 10, a major evolution of the open-source Monte Carlo simulation application for medical physics, built on Geant4. This release marks a transformative evolution, featuring a modern Python-based user interface, enhanced multithreading and multiprocessing capabilities, the ability to be …

fr, nl, at, be, gr, jp, de, pl, us, ca, cz (code pays fourni par la source)

LET spectra scoring for applications in proton radiotherapy

J. Gajewski, Damian Borys, Angelica De Gregorio, Renata Kopeć et autres

Purpose: This work aims at implementation, validation, and proof of application of fast, voxel-based single proton linear energy transfer ( LET ) spectra scoring for clinical proton therapy. The LET spectra provide more comprehensive information on the mixed radiation field produced by …

pl, it, fr, nl (code pays fourni par la source)

GATE 10 Monte Carlo particle transport simulation -- Part II: architecture and innovations

Nils Krah, Nicolas Arbor, Thomas Baudier, Julien Bert et autres

Over the past years, we have developed GATE version 10, a major re-implementation of the long-standing Geant4-based Monte Carlo application for particle and radiation transport simulation in medical physics. This release introduces many new features and significant improvements, most notably a Python-based …

fr (code pays fourni par la source)

GATE 10 Monte Carlo particle transport simulation -- Part I: development and new features

David Sarrut, Nicolas Arbor, Thomas Baudier, Julien Bert et autres

We present GATE version 10, a major evolution of the open-source Monte Carlo simulation application for medical physics, built on Geant4. This release marks a transformative evolution, featuring a modern Python-based user interface, enhanced multithreading and multiprocessing capabilities, the ability to be …

fr (code pays fourni par la source)

optiGAN: a deep learning-based alternative to optical photon tracking in Python-based GATE (10+)

Guneet Mummaneni, Carlotta Trigila, Nils Krah, David Sarrut et autres

Abstract Objective. To accelerate optical photon transport simulations in the GATE medical physics framework using a generative adversarial network (GAN), while ensuring high modeling accuracy. Traditionally, detailed optical Monte Carlo methods have been the gold standard for modeling photon interactions in detectors, …

us, fr, cz (code pays fourni par la source)