Manuel Jesús Romero-Jiménez

Late prolonged cardiac monitoring after cryptogenic ischemic stroke using a textile wearable Holter

José María Fernandez Velasco, Hayar El Mouhajir Mohamed, Francisco Navarro, José Antonio Fermín Marrero et autres

Subclinical atrial fibrillation is a leading underlying cause of cryptogenic stroke. Early prolonged cardiac monitoring is recommended, yet timely access is often limited. We evaluated the performance and therapeutic implications of prolonged cardiac monitoring using the NUUBO ® wearable system in routine …

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Risk factors for atherosclerotic cardiovascular disease in individuals with heterozygous familial hypercholesterolemia: a systematic review and meta-analysis

María Elena Mansilla-Rodríguez, José Luis Sánchez‐Ramos, Alina Rigabert Sánchez-Junco, Jing Pang et autres

BACKGROUND AND AIMS: Familial hypercholesterolemia (FH) is a highly prevalent monogenic disorder characterized by elevated low-density lipoprotein-cholesterol (LDL-C) levels and premature atherosclerotic cardiovascular disease (ASCVD). The risk factors associated with cardiovascular events in this population vary considerably among studies. This systematic review …

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Ticagrelor versus clopidogrel in patients with chronic coronary syndrome undergoing percutaneous coronary intervention: A propensity score-matched analysis

Ignacio Gallo, Gloria Heredia, Rafael Gonzalez-Manzanares, Cristina Urbano et autres

This study aimed to evaluate the efficacy and safety of ticagrelor-based dual antiplatelet therapy (DAPT) compared to clopidogrel-based DAPT in patients with chronic coronary syndrome (CCS) undergoing elective percutaneous coronary intervention (PCI) in a real-world setting. This was a retrospective, single-centre study …

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External validation of the SAFEHEART risk equation for predicting cardiovascular events in Australian patients with familial hypercholesterolaemia

María Elena Mansilla-Rodríguez, Manuel Jesús Romero-Jiménez, Jing Pang, Dick C. Chan et autres

María Elena Mansilla-Rodríguez, Manuel Jesús Romero-Jiménez, Jing Pang, Dick C Chan, Eva Nadiejda Gutiérrez-Cortizo, Pedro Mata, José Luis Sánchez-Ramos, G

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Contractility governs cardiomyocyte cell cycle activity

Nancy Shehata, Rajiven Srikantharajah, Christoph Manthey, Tim Stüdemann et autres

Abstract The heart’s rhythmic contractions keep blood flowing to deliver the oxygen and nutrients that sustain life, but this very strength may also explain why the heart has so little capacity to regenerate. Whereas embryonic and neonatal hearts can repair themselves, this …

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HDL and cardiovascular risk

Manuel Jesús Romero-Jiménez

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Total Cholesterol Determination Accuracy in Dried Blood Spots

Elena Bonet Estruch, María J. López-Lara, Eva Nadiejda Gutiérrez-Cortizo, Miguel Ángel Castaño‐López et autres

Background Detecting total cholesterol in dried blood spots could aid in identifying individuals with a high likelihood of familial hypercholesterolemia and could be used as a screening measure. This study aims to assess the diagnostic accuracy of dried blood spots on Whatman …

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Long-term sex differences in atherosclerotic cardiovascular disease in individuals with heterozygous familial hypercholesterolaemia in Spain: a study using data from SAFEHEART, a nationwide, multicentre, prospective cohort study

Leopoldo Pérez de Isla, Antonio J. Vallejo‐Vaz, Gerald F. Watts, Ovidio Muñiz-Grijalvo et autres

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Total Cholesterol Determination Accuracy in Dried Blood Spots

Elena Bonet Estruch, María J. López-Lara, Eva Nadiejda Gutiérrez-Cortizo, Miguel Ángel Castaño‐López et autres

BACKGROUND Detecting total cholesterol in dried blood spots could aid in identifying individuals with a high likelihood of familial hypercholesterolemia and could be used as a screening measure. This study aims to assess the diagnostic accuracy of dried blood spots on Whatman …

es, us (code pays fourni par la source)

Predictors of cardiovascular risk in familial hypercholesterolemia

Manuel Jesús Romero-Jiménez, María Elena Mansilla-Rodríguez

PURPOSE OF REVIEW: Familial Hypercholesterolemia is associated with an increased risk of cardiovascular disease. The current international guidelines of the main scientific societies consider that all people with familial hypercholesterolemia have a high or very high cardiovascular risk. However, the occurrence of …

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Characteristics of Coronary Atherosclerosis Related to Plaque Burden Regression During Treatment With Alirocumab: The ARCHITECT Study

Leopoldo Pérez de Isla, José Luis Díaz-Díaz, Manuel Jesús Romero-Jiménez, Ovidio Muñiz-Grijalvo et autres

BACKGROUND: Intensive lipid-lowering therapy may induce coronary atherosclerosis regression. Nevertheless, the factors underlying the effect of lipid-lowering therapy on disease regression remain poorly characterized. Our aim was to determine which characteristics of atherosclerotic plaque are associated with a greater reduction in coronary …

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Predictors of cardiovascular risk in familial hypercholesterolemia

Manuel Jesús Romero-Jiménez, María Elena Mansilla-Rodríguez, Eva Nadiejda Gutiérrez-Cortizo

PURPOSE OF REVIEW: Familial hypercholesterolemia is associated with an increased risk of cardiovascular disease. The current international guidelines of the main scientific societies consider that, all people with Familial Hypercholesterolemia have a high or very high cardiovascular risk. However, the occurrence of …

es (code pays fourni par la source)