Trine Bjøro

Changes in serum TSH across the adult lifespan: 22-year follow-up of the HUNT Study

Bjørn Olav Åsvold, Marion Denos, Peter Nicholas Taylor, Salman Razvi et autres

Abstract Objective Some evidence suggests that higher serum TSH may be a part of normal aging, but current studies are limited to 13-year follow-up. We examined TSH changes during 22 years of follow-up across the adult lifespan. Design Longitudinal analyses of the …

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Ethanol Ablation of Metastatic Lymph Nodes in Patients With Papillary Thyroid Carcinoma—Predictors of Clinical Outcome

Pål Stefan Frich, Eva Sigstad, Audun Elnaes Berstad, Else Marie Opsahl et autres

CONTEXT: Ethanol ablation (EA) is a treatment option in recurrent or persistent metastatic lymph nodes (MLNs) from papillary thyroid carcinoma. OBJECTIVE: This work aimed to assess whether ultrasonographic characteristics of the MLN, history of lymph node surgery, aggressive histological subtype, or BRAFV600E …

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Managing hemolysis in serum neuron-specific enolase measurements – an automated algorithm for routine practice

Ragnhild V. Nome, Elisabeth Paus, Johanna Elin Gehin, Nils Bolstad et autres

Neuron-specific enolase (NSE) derived from neurons and peripheral neuroendocrine cells is a biomarker for neuroendocrine tumors and for prognostication in comatose cardiac arrest survivors. However, as platelets and erythrocytes contain NSE, hemolysis causes falsely elevated NSE. We used native serum and hemolysate …

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Associations between patient-reported late effects and systemic cytokines in long-term survivors of head and neck cancer treated with radiotherapy

Trang Thi Huynh, Hans Christian D. Aass, Ragnhild Sørum Falk, Guro Lindviksmoen Astrup et autres

PURPOSE: Head and neck cancer (HNC) treatment may lead to late effects and impaired health-related quality of life of survivors. Knowledge on long-term late effects after radiotherapy (RT) and potential underlying biological mechanisms is lacking. We assessed the prevalence of xerostomia, dysphagia, …

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Long-Term Efficacy of Ethanol Ablation as Treatment of Metastatic Lymph Nodes From Papillary Thyroid Carcinoma

Pål Stefan Frich, Eva Sigstad, Audun Elnaes Berstad, Kristin Holgersen Fagerlid et autres

CONTEXT: Ethanol ablation (EA) is considered an alternative to surgery for metastatic lymph nodes from papillary thyroid carcinoma (PTC) in selected patients. OBJECTIVE: The aim of this study was to evaluate the long-term efficacy and safety of this treatment. DESIGN AND SETTING: …

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Thyroid hypofunction in aging testicular cancer survivors

Ragnhild V. Nome, Milada Cvancarova Småstuen, Sophie D. Fosså, Cecilie Essholt Kiserud et autres

PURPOSE: depth in testicular cancer survivors (TCSs). We investigated the prevalence of thyroid hypofunction in long-term TCSs and compared the findings with those of a comparison group from the general population. PATIENTS AND METHODS: = 1,436) were grouped according to their cancer …

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Rheumatoid factor and falsely elevated results in commercial immunoassays: data from an early arthritis cohort

Johanna Elin Gehin, Rolf Anton Klaasen, Ellen Sauar Norli, David John Warren et autres

The aim of the study was to assess RF cross-reactivity to animal antibodies used in immunoassays, and to test if selected commercial immunoassays are vulnerable to interference from RF, causing false test results. Our study included samples from patients with RF-positive rheumatoid …

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Serum golimumab concentration and anti-drug antibodies are associated with treatment response and drug survival in patients with inflammatory joint diseases: data from the NOR-DMARD study

JE Gehin, DJ Warren, SW Syversen, Elisabeth Lie et autres

Objectives: This study aimed to identify the therapeutic target concentration and frequency of anti-drug antibodies (ADAbs) in golimumab-treated patients with inflammatory joint disease (IJD).Method: Associations between golimumab concentration, ADAbs, and treatment response were examined in 91 patients with IJD [41 axial spondyloarthritis …

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Kjell Johannes Nustad

Elisabeth Paus, Kari Hauge Olsen, David John Warren, Nils Bolstad et autres

FRI0536 SERUM GOLIMUMAB CONCENTRATIONS AND ANTI-DRUG ANTIBODIES ARE ASSOCIATED WITH TREATMENT RESPONSE AND DRUG SURVIVAL IN PATIENTS WITH INFLAMMATORY JOINT DISEASES: DATA FROM THE NOR-DMARD STUDY

Johanna Elin Gehin, D. J. Warren, Silje W Syversen, Elisabeth Lie et autres

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Longitudinal kidney function outcome in aging testicular cancer survivors

Ragnhild V. Nome, Milada Cvancarova Småstuen, Trine Bjøro, Cecilie Essholt Kiserud et autres

Purpose: Testicular cancer survivors (TCSs) have increased risk of reduced kidney function related to treatment burden, but longitudinal studies of renal outcome in aging TCSs have been lacking. This longitudinal study describes age- and treatment-related kidney function changes in TCSs compared to …

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Longitudinal kidney function outcome in aging testicular cancer survivors

Ragnhild V. Nome, Milada Cvancarova Småstuen, Trine Bjøro, Cecilie Essholt Kiserud et autres

Purpose: Testicular cancer survivors (TCSs) have increased risk of reduced kidney function related to treatment burden, but longitudinal studies of renal outcome in aging TCSs have been lacking. This longitudinal study describes age- and treatment-related kidney function changes in TCSs compared to …