Loretto J Carvajal

Trends in Incidence Rates of Anogenital Cancers in Costa Rica, 1996–2022

Loretto J Carvajal, Jaimie Z. Shing, Juan Carlos Vanegas, Rebeca Ocampo et autres

Human papillomavirus (HPV) is the necessary cause of cervical cancer and responsible for ~90% of anal, 78% of vaginal, 50% of penile, and 25% of vulvar cancers. In Costa Rica (CR), few studies have examined incidence trends of these cancers. We assessed …

cr, us (code pays fourni par la source)

Noninferiority of One HPV Vaccine Dose to Two Doses

Aimée R. Kreimer, Carolina Porras, Danping Liu, Allan Hildesheim et autres

BACKGROUND: Multidose human papillomavirus (HPV) vaccination is efficacious, yet the vaccine has been underused globally. Emerging data suggest that a single dose may provide protection. Whether a single dose of HPV vaccine would provide similar protection to two doses is uncertain. METHODS: …

us, cr, fr (code pays fourni par la source)

Knowledge that HPV can cause oropharyngeal cancer and cervical cancer among adults in the United States: A comparison of prevalence and predictors

Iriana Peña-Manrique, Beth J. Maclin, Aimée R Kreimer, Hosam Alraqiq et autres

us, cr (code pays fourni par la source)

Design and initial findings of a natural history study of anal HPV and associated lesions among young adult women in Costa Rica

Cameron B. Haas, Rebeca Ocampo, Danping Liu, Michael Zúñiga et autres

Anal cancer is caused by HPV, and its incidence has increased globally over the last five decades. We conducted an anal HPV natural history study nested in the Costa Rica HPV Vaccine Trial (CVT) to quantitatively describe the natural history and clinical …

us, cr (code pays fourni par la source)

Descriptive epidemiology of gastric cancer in Costa Rica from 1990 to 2022 and projection of deaths to 2050: a population-based study

Rolando Herrero, Cristina Barboza‐Solís, Rebeca Ocampo, Guillermo Torres et autres

Background: In Costa Rica, gastric cancer has been the leading cause of cancer death (both sexes) since the 1980s. The objective of this study was to analyze the incidence, mortality, and geographic distribution of stomach cancer in Costa Rica for the period …

cr (code pays fourni par la source)

Human papillomavirus (HPV) type 16 and type 18 antibody concentrations after a single dose of bivalent HPV vaccine in girls aged 9–14 years compared with three doses of quadrivalent HPV vaccine in women aged 18–25 years in Costa Rica (PRIMAVERA): a non-randomised, open-label, immunobridging, non-inferiority trial

Bernal Cortés, Rebeca Ocampo, Carolina Porras, Danping Liu et autres

BACKGROUND: In 2022, WHO recommended single-dose human papillomavirus (HPV) vaccination as an alternative schedule to multidose regimens. To provide evidence to support approval of a single-dose indication for the AS04-adjuvanted bivalent HPV vaccine (Cervarix, GlaxoSmithKline), we investigated whether the immune response to …

cr, us (code pays fourni par la source)

Changes in incidence of HPV-related cancers in South Africa (2011–21): a cross-sectional analysis of the South African National Cancer Registry

Jaimie Z. Shing, Sizeka Mashele, Adino Tesfahun Tsegaye, Bianca Da Costa Dias et autres

BACKGROUND: Understanding human papillomavirus (HPV)-related cancer epidemiology in South Africa is crucial for informing cancer prevention in this high-burden country. We aimed to describe HPV-related cancer incidence in South Africa between 2011 and 2021. METHODS: For this cross-sectional study, we obtained data …

us, ch, Afrique du Sud, cr (code pays fourni par la source)

Human papillomavirus type 16 and 18 viral clearance and progression to precancer among women aged 18–25 years enrolled in the Costa Rica HPV prophylactic vaccine trial (CVT)

Mónica S. Sierra, Loretto J Carvajal, Peter Dull, Rolando Herrero et autres

New approaches to control HPV infections and prevent progression to cervical precancer are needed. We investigate the probability of viral clearance and progression to cervical precancer in women infected with HPV16/18 without evidence of precancer at study enrollment to inform research efforts …

us, cr (code pays fourni par la source)

A surveillance study of cancer incidence and mortality among young adults in Costa Rica

Rachel Slimovitch, Jaimie Z. Shing, Romain Fantin, Juan Carlos Vanegas et autres

Background: There has been an increase in certain cancers among young adults (YA) aged 20-39, particularly in Latin America. This is the first study to examine cancer incidence and mortality in YA in Costa Rica, focusing on sex-specific patterns. Methods: Invasive cancer …

us, cr (code pays fourni par la source)

Differential long-term bivalent HPV vaccine cross-protection by variants in the Costa Rica HPV vaccine trial

Jaimie Z. Shing, Carolina Porras, Maísa Pinheiro, Rolando Herrero et autres

The AS04-adjuvanted human papillomavirus (HPV)16/18 vaccine, an L1-based vaccine, provides strong vaccine efficacy (VE) against vaccine-targeted type infections, and partial cross-protection to phylogenetically-related types, which may be affected by variant-level heterogeneity. We compared VE against incident HPV31, 33, 35, and 45 detections …

us, cr, nl (code pays fourni par la source)

Descriptive Epidemiology of Gastric Cancer in Costa Rica from 1990 to 2022 and Projection of Deaths to 2050

Juan Carlos Vanegas, Rolando Herrero, Rebeca Ocampo, Guillermo Torres et autres

bo, cr (code pays fourni par la source)

Descriptive Epidemiology of Gastric Cancer in Costa Rica from 1990 to 2022 and Projection of Deaths to 2050

Juan Carlos Vanegas, Rolando Herrero, Rebeca Ocampo, Guillermo Torres et autres

bo, cr (code pays fourni par la source)