2026
conference-abstract
OpenAlex
Ashish Samaddar, Alexandra Feathers, Srinivas Govindan, Shuyi Chen et autres
8076 Background: Although cigarette smoking is the main risk factor for lung cancer, 10–20 percent of cases occur in non-smokers, with women disproportionately affected. This pattern suggests that community-level environmental exposures may contribute to lung cancer risk beyond smoking. Methods: In this …
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2026
article
OpenAlex
Ethan Paul Royka, Chase A. Shipp, Nhi D. Nguyen, Phyu Thin Naing et autres
e13502 Background: Racial, ethnic, and linguistic minorities remain underrepresented in clinical trials. While structural barriers to enrollment are well documented, patient perceptions and cultural factors influencing participation remain understudied. This study aims to assess patient perceptions and barriers to trial participation and …
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2026
conference-abstract
OpenAlex
Wint Yan Aung, Divya Chukkalore, NEHEMIAS GUEVARA, Nina Cheranda et autres
e20766 Background: Approximately 20% of EGFR-mutant metastatic non-small cell lung cancer (NSCLC) presents as recurrent disease in real-world practice. Whether metastatic presentation (de novo vs recurrent) influences treatment durability and disease control on first-line (1L) EGFR tyrosine kinase inhibitors (TKIs) is unknown. …
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2026
conference-abstract
OpenAlex
Juliet Meir, Divya Chukkalore, Wint Yan Aung, NEHEMIAS GUEVARA et autres
e20685 Background: Older adults with EGFR-mutant metastatic non-small cell lung cancer (NSCLC) are underrepresented in clinical trials, and treatment decisions often rely on chronological age rather than biologic reserve. Whether vulnerability modifies the relationship between age and real-world treatment outcomes remains unknown. …
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Accès ouvert
2026
article
OpenAlex
Monica Wallin, Juliet Meir, Teshmanie Rampersaud, Sally Ko et autres
e19055 Background: Patients (pts) with diffuse large B-cell lymphoma (DLBCL) who are elderly, frail, or have cardiac comorbidities are frequently ineligible for anthracycline-based chemotherapy and are underrepresented in clinical trials. Chemotherapy-sparing regimens incorporating antibody–drug conjugates and immunomodulatory agents may provide an alternative …
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2025
conference-abstract
OpenAlex
Juliet Meir, Adrian Choppa, Shuyi Chen, Nagashree Seetharamu
498 Background: NGS remains underutilized in early-stage NSCLC which results in missed opportunities to personalize therapy. Timely molecular profiling is critical to ensure actionable results are available prior to multidisciplinary planning. Institutional studies suggest that preoperative NGS on biopsy specimens does not …
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2025
conference-abstract
OpenAlex
Phyu Thin Naing, Kelvin Zheng, Divya Chukkalore, Richa Thakur et autres
Abstract Background: Racial disparities in incidence, mortality, and access to care persist in multiple myeloma (MM). Black/African Americans remain underrepresented in pivotal clinical trials, such as MAIA and PERSEUS, that led to the approval of novel agents like daratumumab (Dara). Dara received …
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Accès ouvert
2024
article
OpenAlex
Andy Wang, Juliet Meir, Aaqib H. Malik, Tzvi Fishkin et autres
Coronary vasospasm can lead to decreased cardiac perfusion and result in acute coronary syndrome. Here is a case of a 49-year-old man presented to the emergency department with epigastric pain and nausea with normal initial electrocardiogram. However, 6 h later, the patient …
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2024
article
OpenAlex
Lillian Huang, Juliet Meir, William H. Frishman, Wilbert S. Aronow
This review examines the complex bidirectional relationship between cardiovascular disease and various dementia subtypes, including Alzheimer's disease, vascular dementia, Lewy body dementia, and frontotemporal dementia. Traditional cardiovascular risk factors such as hypertension, coronary artery disease, arrhythmia, and diabetes mellitus are strongly linked …
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2023
article
OpenAlex
Juliet Meir, Lillian Huang, Sumaita Mahmood, Harris Z. Whiteson et autres
INTRODUCTION: This review highlights the pathogenesis of both microvascular and macrovascular complications of diabetes and how these mechanisms influence both the management and preventative strategies of these complications. The cumulative data shown in this review suggest hyperglycemic and blood pressure control remain …
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Accès ouvert
2023
article
OpenAlex
Yagya Ahlawat, Juliet Meir, C. Benjamin, Amir Steinberg
A 29-year-old male, hemodynamically stable, presented with chest pain radiating to the interscapular region, with no fever, cough, dyspnea, or other constitutional symptoms. He had right cervical lymphadenopathy on physical examination. Investigations revealed a 3.1 cm anterior mediastinal nodular mass, peripheral immature …
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2023
article
OpenAlex
Liana Michaud, Matthew Seplowe, Juliet Meir, Wilbert S. Aronow
INTRODUCTION: There are three major drug classes discussed in this review: dipeptidyl dipeptidase-4 (DPP4) inhibitors, glucagon-like peptide-1 receptor agonists (GLP-1 RAS), and sodium-glucose cotransporter-2 (SGLT2) inhibitors. A literature review of the landmark cardiovascular outcome trials from 2008 to 2021 was conducted. AREAS …
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