Hao‐Yu Liu

Lactobacillus johnsonii N5 Supernatant Protects RPMI-2650 Cells from HDM-Induced Injury in Association with Suppression of the NR4A1–IRE1–XBP1-Mediated Unfolded Protein Response

Wei Ma, Yufei Chen, Yaxin Feng, Long Yuan et autres

Background/Objectives: House dust mites (HDMs) are significant allergens that cause damage to nasal epithelial cells and have a role in the pathophysiology of allergic rhinitis. Lactobacillus johnsonii N5 supernatant (N5sup), a probiotic strain, exhibits possible protective properties; nevertheless, the molecular processes involved …

cn (code pays fourni par la source)

Eicosapentaenoic Acid (EPA) Alleviates Oxidative Stress and Inflammatory Responses in Canine Ileal Epithelial Cells

Xiaoyue Yuan, Xizhu Zhu, Chuyang Zhu, Yunhan Wang et autres

Fueled by the rapid growth of the global companion animal industry, the development of nutritional additives for improving canine intestinal health has emerged as a prominent research area in pet nutrition. Excessive reactive oxygen species accumulation triggers severe oxidative stress, inducing intestinal …

cn (code pays fourni par la source)

Probiotic Lactobacillus johnsonii Reduces Intestinal Inflammation and Rebalances Splenic Treg/Th17 Responses in Dextran Sulfate Sodium-Induced Colitis

Hao‐Yu Liu, Shicheng Li, Kennedy Jerry Ogamune, Peng Yuan et autres

Inflammatory bowel disease (IBD), a chronic inflammatory disorder of the gastrointestinal tract, is frequently complicated by extraintestinal manifestations such as functional hyposplenism. Increasing evidence highlights its pathogenesis as a multifactorial interplay of gut dysbiosis, intestinal barrier dysfunction, and dysregulated immune responses. While …

cn, Botswana, kr (code pays fourni par la source)

Lithocholic acid attenuates DON-induced inflammatory responses via epigenetic regulation of DUSP5 and TRAF5 in porcine intestinal epithelial cells

Shiqi Wang, Xiaoxu Peng, Qi Zhu, Shibi Lu et autres

Deoxynivalenol (DON) is the most common mycotoxin that frequently contaminates human food and animal feed, resulting in intestinal diseases and systemic immunosuppression. Lithocholic acid (LCA) exhibits various pharmacological activities. RNA-seq and ChIP-qPCR analysis were used in the current study to investigate the …

cn, kr (code pays fourni par la source)

Phytogenics in swine nutrition and their effects on growth performance, nutrient utilization, gut health, and meat quality: a review

Madesh Muniyappan, Jinlong Yan, Gao Jinan, Ping Hu et autres

Abstract Phytogenic feed additives have undergone extensive testing in swine production to determine their effects on gastrointestinal function and health, as well as their implications for pigs' systemic health and welfare, flock production efficiency, food safety, and environmental impact. These feed additives …

cn, kr, us (code pays fourni par la source)

Melatonin Modulates ZAP70 and CD40 Transcripts via Histone Modifications in Canine Ileum Epithelial Cells

Jian Hong, Saber Y. Adam, Shiqi Wang, Hao Huang et autres

Melatonin (MLT), produced by the pineal gland and other tissues, is known for its anti-inflammatory effects, particularly in regulating inflammatory markers and cytokines in intestinal cells. Our study aimed to investigate how MLT influences the expression of inflammatory genes through histone modification …

cn, kr, Botswana, Soudan (code pays fourni par la source)

Line Loss Prediction Method for Urban Distribution Networks Based on Optimized RBF and K-means++ Algorithm Under Double Carbon Targets

Zhe Li, Hao‐Yu Liu, Kailun Zhang, Chenyang Tu et autres

The application of digital technology to optimize urban distribution networks and lower carbon emissions has drawn more attention as a result of the dual carbon targets and the quick development of artificial intelligence. In order to reduce the carbon emissions of urban …

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Dietary Organic Zinc Supplementation Modifies the Oxidative Genes via RORγ and Epigenetic Regulations in the Ileum of Broiler Chickens Exposed to High-Temperature Stress

Saber Y. Adam, Madesh Muniyappan, Hao Huang, Wael Ennab et autres

Heat stress (HS) is a significant concern in broiler chickens, which is vital for global meat supply in the dynamic field of poultry farming. The impact of heat stress on the ileum and its influence on the redox homeostatic genes in chickens …

cn, Botswana, Soudan, kr (code pays fourni par la source)

Insights into the interplay between gut microbiota and lipid metabolism in the obesity management of canines and felines

Kaiqi Li, Xiangyu Xiao, Yuling Li, Sichen Lu et autres

Obesity is a prevalent chronic disease that has significant negative impacts on humans and our companion animals, including dogs and cats. Obesity occurs with multiple comorbidities, such as diabetes, hypertension, heart disease and osteoarthritis in dogs and cats. A direct link between …

cn (code pays fourni par la source)

Lithocholic Acid Alleviates Deoxynivalenol-Induced Inflammation and Oxidative Stress via PPARγ-Mediated Epigenetically Transcriptional Reprogramming in Porcine Intestinal Epithelial Cells

Yanwei Li, Chuyang Zhu, Jiacheng Yao, Cuipeng Zhu et autres

Deoxynivalenol (DON) is a common mycotoxin that induces intestinal inflammation and oxidative damage in humans and animals. Given that lithocholic acid (LCA) has been suggested to inhibit intestinal inflammation, we aimed to investigate the protective effects of LCA on DON-exposed porcine intestinal …

cn, Botswana (code pays fourni par la source)

Zinc intake ameliorates intestinal morphology and oxidative stress of broiler chickens under heat stress

Ping Hu, Kaiqi Li, Xiaoxu Peng, Tong-Jia Yao et autres

Zinc (Zn), an essential trace element for poultry, plays a crucial role in promoting growth, improving feed conversion efficiency, enhancing antioxidant activity, and preventing disease. This study investigated the impact of different levels and sources of dietary Zn supplementation on the growth …

cn, Botswana (code pays fourni par la source)

Nutrition, Epigenetics, and Circadian Rhythms

Demin Cai, Hao‐Yu Liu, Kaiqi Li, Yanli Zhu

cn (code pays fourni par la source)