Yan-Hua Lian

Intermittent Theta-Burst Stimulation (iTBS) Improves Motor Coordination and Modulates Neuroinflammation and Autophagy in SCA3/MJD Mice

L.-W. Chen, Yan-Hua Lian, Xiao-Lei Dong, Kai-Liang Luo et autres

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Distribution of perivascular spaces distribution and relate to the clinical features of SCA3

Xinyuan Chen, Yan-Hua Lian, Xiao‐Yue Xia, Lin Zhang et autres

BACKGROUND: Spinocerebellar ataxia type 3 (SCA3) is a rare neurodegenerative condition. Prior research has established perivascular spaces (PVS) expansion has been implicated in the pathogenesis and prognosis of various neurodegenerative diseases. To examine PVS changes in SCA3 by comparing patients and matched …

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Transcranial alternating current stimulation for treating spinocerebellar ataxia type 3: A randomized controlled trial

Xinyuan Chen, Xia Liu, Wei Lin, Lin Zhang et autres

There are no specific treatments for spinocerebellar ataxia type 3 (SCA3), a neurodegenerative disease causing cerebellar dysfunction. Transcranial alternating current stimulation (tACS) can improve cerebellar motor functions, and it has been shown to be safe and effective in treating neurological diseases. This …

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Neuroimaging mechanisms of low-frequency repetitive transcranial magnetic stimulation for treatment of SCA3/MJD: a double-blind randomized sham-controlled trial

Xinyuan Chen, Lin zhang, Yan-Hua Lian, Jun Ni

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Case report: Beneficial effects of visual cortex tDCS stimulation combined with visual training in patients with visual field defects

Yan-Hua Lian, Xiaoping Cheng, Qunlin Chen, Libin Huang et autres

Background: Visual field defect (VFD) refers to the phenomenon that the eye is unable to see a certain area within the normal range of vision, which may be caused by eye diseases, neurological diseases and other reasons. Transcranial direct current stimulation (tDCS) …

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Effects of cerebellar transcranial alternating current stimulation in cerebellar ataxia: study protocol for a randomised controlled trial

Xia Liu, Wei Lin, Lin Zhang, Wanli Zhang et autres

Background: Cerebellar ataxia (CA) is a movement disorder that can affect balance and gait, limb movement, oculomotor control, and cognition. Multiple system atrophy-cerebellar type (MSA-C) and spinocerebellar ataxia type 3 (SCA3) are the most common forms of CA, for which no effective …

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Effects of Repetitive Transcranial Magnetic Stimulation on Cerebellar Metabolism in Patients With Spinocerebellar Ataxia Type 3

Xinyuan Chen, Yan-Hua Lian, Xia‐Hua Liu, Arif Sikandar et autres

Background Spinocerebellar ataxia type 3 (SCA3) is the most common autosomal dominant hereditary ataxia, and, thus far, effective treatment remains low. Repetitive transcranial magnetic stimulation (rTMS) can improve the symptoms of spinal cerebellar ataxia, but the mechanism is unclear; in addition, whether …

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