Caiqin Mu

Molecular response of a patient with e19a2-positive chronic myeloid leukemia to flumatinib: a case report and literature review

Yaqing Feng, Hongjin Wang, Lidong Zhang, J Y Gong et autres

Objective Chronic myeloid leukemia (CML) is a malignancy driven by the BCR::ABL1fusion gene, with the e19a2 transcript being a rare variant, accounting for 0.4% of CML cases. Patients with the e19a2 transcript often show poor response to first-line treatment with imatinib, and …

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Clinical study reveals the efficacy of sirolimus in treating primary immune thrombocytopenia: findings from a single-center study

Yaqing Feng, Haitao Meng, Caiqin Mu, Yanfang Zhang et autres

Immune thrombocytopenia (ITP) is an autoimmune disease that arises because of self-destruction of circulating platelets. The mechanism remains complicated and lacks a standard clinical treatment. Current first-line and second-line medications for ITP have shown limited effectiveness, necessitating the exploration of new therapeutic …

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A research on the antiviral treatment of hepatitis C cirrhosis and its related factors

Caiqin Mu, Lu Zhang, Yao Lu, Shuling Wu et autres

Objective To investigate the sustained virological response (SVR) of patients with hepatitis C cirrhosis and its related factors. Method According to their clinical characteristics, 129 patients of hepatitis C cirrhosis were injected Pegasys (Peg-IFNα2a) and ribavirin (15 mg/kg/d). The serum HCV RNA …

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Hepatitis B surface antigen clearance in inactive hepatitis B surface antigen carriers treated with peginterferon alfa-2a

Minghui Li, Yao Xie, Lu Zhang, Yao Lu et autres

AIM: To examine the association between interferon (IFN) therapy and loss of hepatitis B surface antigen (HBsAg) in inactive HBsAg carriers. METHODS: This was a retrospective cohort study in inactive HBsAg carriers, who were treatment-naive, with a serum HBsAg level < 100 …

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[Efficacy of pegylated-interferon alpha-2a treatment in patients with HBeAg-positive chronic hepatitis B and partial viral response to nucleoside analogue therapy].

Minghui Li, Leiping Hu, Lu Zhang, Yao Lu et autres

OBJECTIVE: To investigate the efficacy and related factors of pegylated-interferon alpha-2a (PEG-IFN-2a) treatment in patients with hepatitis B e antigen (HBeAg)-positive chronic hepatitis B (CHB) who achieved partial viral response with nucleoside analogue (NA) therapy. METHODS: Patients with HBeAg-positive CHB and partial …

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Dynamic changes of acute hepatitis B serologic and virologic markers

Julong Hu, Leiping Hu, Lu Zhang, Caiqin Mu et autres

Objective To analyze the dynamic changes of the clinical characteristics and virology of acute hepatitis B and the pathological characteristics and to investigate the clinical features and prognosis of acute hepatitis B.Methods Analysis was performed on the serology and virology of 155 …

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The efficacy of antiviral treatment with nucleus (t)ide analogues during the entire pregnancy

Luxue Zhang, Caiqin Mu, Minghui Li, Yao Xie

Objective To investigate the efficacy of antiviral treatment with nucleus (t) ide analogues during the entire pregnancy.Method The clinical data were collected from pregnant women with nucleus(t) ide analogues during the entire pregnancy in Beijing Ditan Hospital from 2009 to 2013,including HBV …

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[Analyse related factors of impact and prognosis of 73 cases of severe hepatitis].

Junmei Zhao, Lu Zhang, Qing-Wei Du, Caiqin Mu et autres

OBJECTIVE: A retrospective study was conducted to investigate the clinical features and prognostic factors of 73 cases of severe hepatitis. METHODS: To summarize clinical features of 73 cases of severe hepatitis, grouping by etiology and pathogenesis. A retrospective analysis was performed to …

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[Study on the etiology of acute hepatitis hospitalized patients in Beijing Ditan Hospital from 2002 to 2011].

Ge Shen, Lu Zhang, Yanli Zhang, Leiping Hu et autres

OBJECTIVE: To explore the etiology of acute hepatitis hospitalized patients in Beijing Ditan Hospital from 2002 to 2011. METHODS: We summed up the changes in the characteristics of the etiology of acute hepatitis of patients mentioned above, and preliminarily analyze the causes. …

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The Predictive Value of On-treatment Virological Response for Sustained Virological Response in Chronic Hepatitis C Patients Receiving a Personalized Treatment Program

Minghui Li, Yao Xie, Yao Lu, Guo‐Hua Qiu et autres

Abstract Objective To investigate the effects of individualised treatment with peginterferon alpha-2a (40 kD) plus ribavirin in Chinese patients with CHC. Methods Total of 297 consecutive Chinese patients were enrolled, including 250 naïve cases and 47 cases who were previously treated. Treatment …

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Clinical analysis on 10 patients with hepatic myelopathy

Caiqin Mu

Objective To explore more details about the pathogenesis and imaging features of hepatic myelopathy (HM). Methods Ten patients with HM were enrolled in this study. The clinical data were investigated, retrospectively. Results There were eight cases with hepatitis B and two cases …