Yakov Lapitsky

Algaecide-Releasing Buoys for Sustained Harmful Algal Bloom Control

Umberto A. Kober, Haniehsadat Barikbin, Young‐Woo Seo, Yakov Lapitsky

High Resolution Image Download MS PowerPoint Slide Cyanobacterial harmful algal bloom (CHAB) management is challenging, costly, and often requires repeated algaecide application. To this end, here we develop and characterize reusable buoy-like devices that can sustain algaecide release over periods exceeding one …

us (code pays fourni par la source)

Immunomodulation Through Fibroblast-Derived Extracellular Vesicles (EVs) Within 3D Polycaprolactone–Collagen Matrix

Afsara Tasnim, Diego Jacho, Agustín Rabino, Jose Benalcazar et autres

Extracellular vesicles (EVs) have emerged as promising acellular tools for modulating immune responses for tissue engineering applications. This study explores the potential of human fibroblast-derived EVs delivered within a three-dimensional (3D) injectable scaffold composed of polycaprolactone (PCL) nanofibers and collagen (PNCOL) to …

us (code pays fourni par la source)

Toward Wet Wipes That Turn into Toilet Paper Debris When Flushed Through Reversible Biopolyelectrolyte Self-Assembly

Kunal Choudhuri, Reece C. Kendall, Michael D. Griffin, Umberto A. Kober et autres

Wet wipes are widely used in cleaning and personal hygiene applications. However, they frequently contain plastic components that cause microplastic pollution and, even when marketed as flushable, have, in the case of many tested products, been found to agglomerate and clog pipes …

us, ca (code pays fourni par la source)

Transforming the Stability, Encapsulation, and Sustained Release Properties of Calcium Alginate Beads through Gel-Confined Coacervation

Oluwadamilola I. Egbeyemi, Wesam A. Hatem, Umberto A. Kober, Yakov Lapitsky

Calcium alginate (Ca 2+ /alginate) gel beads find use in diverse applications, ranging from drug delivery and tissue engineering to bioprocessing, food formulation, and agriculture. Unless modified, however, these gels have limited stability in alkaline media (including phosphate buffers), and their high …

us (code pays fourni par la source)

Smart exosomes enhance PDAC targeted therapy

Justin F. Creeden, Jonathan Sevier, Jian‐Ting Zhang, Yakov Lapitsky et autres

Exosomes continue to attract interest as a promising nanocarrier drug delivery technology. They are naturally derived nanoscale extracellular vesicles with innate properties well suited to shuttle proteins, lipids, and nucleic acids between cells. Nonetheless, their clinical utility is currently limited by several …

us (code pays fourni par la source)

Bicarbonate-mediated dissolution of chitosan-based polyelectrolyte complex gels

Kunal Choudhuri, Gabrielle M. Blevins, Umberto A. Kober, Yakov Lapitsky

us (code pays fourni par la source)

Accelerating Payload Release from Complex Coacervates through Mechanical Stimulation

Wesam A. Hatem, Yakov Lapitsky

Complex coacervates formed through the association of charged polymers with oppositely charged species are often investigated for controlled release applications and can provide highly sustained (multi-day, -week or -month) release of both small-molecule and macromolecular actives. This release, however, can sometimes be …

us (code pays fourni par la source)

Preparation of polyelectrolyte complex nanoparticles with tunable and narrow size distributions by template polymerization

Kunal Choudhuri, Joshua D. Bastian, Jeremiah T. Berger, Udaka K. de Silva et autres

us (code pays fourni par la source)

Poly(allylamine)/tripolyphosphate coacervates for encapsulation and long-term release of cetylpyridinium chloride

Sabrina S. Alam, Carolina B. Mather, Young‐Woo Seo, Yakov Lapitsky

us (code pays fourni par la source)

Surfactant-loaded Polyelectrolyte/multivalent Ion Coacervates for the Multi-month Release of Antibacterial and Therapeutic Payloads

Yakov Lapitsky, Sabrina S. Alam, Udaka K. de Silva, Jennifer Brown et autres

Highly Sustained Release of Bactericides from Complex Coacervates

Sabrina S. Alam, Young‐Woo Seo, Yakov Lapitsky

Materials for preventing harmful bacterial contamination attract widespread interest in areas that include healthcare, home/personal care products, and crop protection. One approach to achieving this functionality is through the sustained release of antibacterial compounds. To this end, we show how putty-like complex …

us (code pays fourni par la source)

Biomolecular uptake effects on chitosan/tripolyphosphate micro- and nanoparticle stability

Yuhang Cai, Yakov Lapitsky

us (code pays fourni par la source)