Mingmei Ye

The impact of sex on the efficacy of anti-TNF-α therapy in Crohn’s disease patients with different visceral adipose tissue levels

Yuanyuan Huang, Zili Xiong, Weiwei Zhou, Hongbing Zhou et autres

Sex, location, and visceral adipose tissue (VAT) influence the course of Crohn’s disease (CD). However, the combined impact of these factors has not been consistently or thoroughly considered in anti-tumour necrosis factor-α (anti-TNF-α) therapy. This study aims to investigate how sex, location, …

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P0926 Does Intestinal Ultrasound Combined with Visceral Adipose Tissue more Accurately Predict Primary Non-response to Infliximab in Patients with Crohn’s Disease? A Prospective, Observational Study

Mingmei Ye, P Zhao, F Gao, Y Mei et autres

Abstract Background Infliximab (IFX) is widely used for the treatment of Crohn’s disease (CD), yet up to 40% patients experience primary non-response (PNR). Visceral adipose tissue and intestinal ultrasound (IUS) could be used as noninvasive tools to predict treatment efficacy with limited …

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Does intestinal ultrasound combined with visceral adipose tissue more accurately predict primary non-response to infliximab in patients with Crohn’s disease? A prospective, observational study

Mingmei Ye, Panpan Zhao, Feng Gao, Ying Mei et autres

Background: Infliximab (IFX) is widely used for the treatment of Crohn’s disease (CD), yet up to 40% patients experience primary non-response (PNR). Visceral adipose tissue (VAT) and intestinal ultrasound (IUS) could be used as noninvasive tools to predict treatment efficacy with limited …

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Machine learning-based prediction of response to Ustekinumab with Crohn’s disease

Ziyi Xiong, Pan Gong, Mingmei Ye, Yuanyuan Huang et autres

Background: A reliable approach to predict the response to Ustekinumab (UST) in patients with Crohn's disease (CD) is lacking. Objectives: This study aims to develop and validate machine learning (ML) models to predict the response to UST and further achieve personalized therapy. …

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Diagnostic yield and safety of pancreatic cystic lesions: A comparison between EUS-FNA and EUS-FNB.

Xiaoyu Yu, Mingmei Ye, Yongnian Ni, Qianqi Liu et autres

OBJECTIVES: In recent years, the incidence and detection rate of pancreatic cystic lesions (PCLs) have increased significantly. Endoscopic ultrasound (EUS) plays an indispensable role in the diagnosis and differential diagnosis of PCLs. However, evidence comparing the diagnostic performance of EUS-guided fine-needle aspiration …

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EUS-led breakthrough: An innovative journey to overcome complete gastric outlet obstruction by gastroenterostomy (with video)

Yuanyuan Yang, Mingmei Ye, Xiaoyan Wang, Tian Li

EUS-guided gastroenterostomy (EUS-GE) is a new option for palliation of malignant gastric outlet obstruction (GOO), with minimal surgical trauma, high success rate, and excellent clinical outcomes.[1–4] Usually, it is necessary to identify the target intestinal lumen and distend it. What should be …

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Emergency Pancreatic Pseudocyst Exploration to Retrieve a Stent: A Nerve-Wracking Migration

Mingmei Ye, 豊 大根田, Ying Zhong, Li Tian

Ye, Mingmei MM1,*; Liu, Quanheng BM1,*; Zhong, Ying MM2,a; Tian, Li MD, PhD1,a Author Information

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A scale to measure the worry level in Gastrointestinal Endoscopy with sedation: Development, reliability, and validity

Xiaoyu Yu, Haijun Deng, Ziyi Xiong, Pan Gong et autres

Objective: This study aims to develop a scale to measure the worry level of patients who will undergo gastrointestinal (GI) endoscopy with deep sedation, and to provide scientific references to alleviate their worries. Method: Based on literature review, panel discussion, patient interview …

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Microcystin-LR Induces and Aggravates Colitis through NLRP3 Inflammasome-Mediated Pyroptosis in Mice

Yue Yang, Pan Gong, Xiuyan Long, Yuanjuan Jiang et autres

Inflammatory bowel disease (IBD) is a chronic, lifelong gastrointestinal disease, characterized by periods of activity and remission. The etiology of IBD is closely related to environmental factors. Previous studies have shown that the cyanotoxin microcystin-LR (MC-LR) causes intestinal damage, even IBD. To …

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Endoscopic ultrasound diagnosis system based on deep learning in images capture and segmentation training of solid pancreatic masses

Anliu Tang, Pan Gong, Ning Fang, Mingmei Ye et autres

BACKGROUND: Early detection of solid pancreatic masses through contrast-enhanced harmonic endoscopic ultrasound (CH-EUS) is important. But CH-EUS is difficult to learn. PURPOSE: To design a deep learning-based CH-EUS diagnosis system (CH-EUS MASTER) for real-time capture and segmentation of solid pancreatic masses and …

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A Scale to Measure the Worry Level in Gastrointestinal Endoscopy with Sedation: Development, Reliability, and Validity

Xiaoyu Yu, Haijun Deng, Ziyi Xiong, Pan Gong et autres

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Effects of visceral adipose tissue on anti-tumour necrosis factor-α in Crohn’s disease

Kangrong Li, Pan Gong, Yongbin Zhang, Minji Liu et autres

Background: It remains unclear whether visceral adipose tissue (VAT) can predict the response of patients with Crohn’s disease (CD) to anti-tumour necrosis factor-α (anti-TNF-α) therapy. Objectives: This study aimed to investigate whether VAT predicts the efficacy of infliximab (IFX) for different sites …

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