Quang Minh Dang

mRNA profiling of mesenchymal stem cell-derived exosomes reveals their function in accelerating wound healing

Uyen Thi Trang Than, Hoai Thi Thanh Nguyen, Quang Minh Dang, Thu-Huyen Nguyen et autres

Extracellular vesicles (EVs) are emerging as innovative tools for regenerative and therapeutic applications, including wound healing, owing to their ability to encapsulate bioactive agents from their parent cells. In this study, we profiled the transcriptome of umbilical cord mesenchymal stem cell (UCMSC)-derived …

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Hepatocyte growth factor as a driver of synovial inflammation and therapeutic resistance in rheumatoid arthritis

Quang Minh Dang, Ryu Watanabe, Takeshi Iwasaki, Ryuhei Ishihara et autres

Background Previous studies have demonstrated that hepatocyte growth factor (HGF) is implicated in treatment resistance in rheumatoid arthritis (RA). This study aimed to elucidate the mechanistic role of HGF in synovial inflammation and assess the therapeutic potential of targeting the HGF-c-Met axis. …

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mRNA profiling of mesenchymal stem cell-derived exosomes reveals their function in accelerating wound healing

Uyen Thi Trang Than, Hoai Thi Thanh Nguyen, Quang Minh Dang, Thu-Huyen Nguyen et autres

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8P Next generation topoisomerase I inhibitors as novel ADC payloads to overcome resistance to ADC with camptothecin-based payloads

Quang Minh Dang, Xin Fu, Yi Li, Qi Wang et autres

Recent breakthrough discoveries of ADCs such as DS-8201 attracted more attention to TOPO-1 inhibitors, however most if not all payloads targeting TOPO-1 still utilized the original CPT core (e.g. DXD, SN-38). One common concern is that these ADC treatments will eventually lead …

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Multi-stage-mixing to control the supramolecular structure of lipid nanoparticles, thereby creating a core-then-shell arrangement that improves performance by orders of magnitude

Jia Nong, Xijing Gong, Quang Minh Dang, Sachchidanand Tiwari et autres

As they became the dominant gene therapy platform, lipid nanoparticles (LNPs) experienced nearly all their innovation in varying the structure of individual molecules in LNPs. This ignored control of the spatial arrangement of molecules, which is suboptimal because supramolecular structure determines function …

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Osteosarcoma patient with Li-Fraumeni syndrome: the first case report in Vietnam

Thanh T. Le, Tung Sy Ha, Linh To, Quang Minh Dang et autres

Li–Fraumeni syndrome (LFS) is a hereditary disorder characterized by an increased risk of developing multiple early-onset cancers, primarily due to germline TP53 mutations. Women and men with this mutation face lifetime cancer risks of 90% and 70%, respectively. This report describes the …

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Auto-proctoring using computer vision in MOOCs system

Tuan Linh Dang, Nguyen Minh Nhat Hoang, The Vu Nguyen, Hoang Vu Nguyen et autres

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A lightweight approach for image quality assessment

Quang Minh Dang, Minh Tuyen Truong, Tuan Linh Dang

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DATE: a video dataset and benchmark for dynamic hand gesture recognition

Tuan Linh Dang, Duc Manh Dao, Hoang Vu Nguyen, Quang Minh Dang et autres

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110P The relationship between tumor necrosis, histopathology type, and preoperative chemotherapy regimens in patients with osteosarcoma

Kinh Van Nguyen, Hang. T. T. Tran, Toan Tran Duc, Quang Minh Dang et autres

Our research aimed to investigate the potential correlations between the extent of tumor necrosis and various factors, such as histopathological types, preoperative chemotherapy regimens, and other factors, in high-grade osteosarcoma patients treated at our institution.

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128P Innovative limb salvage: Liquid nitrogen approach in reconstruction after bone tumor resection

Quang Minh Dang, S.Q. Nguyen Tran Quang, Toan Tran Duc, Tran Van Chen et autres

Osteosarcoma is the most common primary malignant bone tumor in children and adolescents. Various techniques for reconstructing bone and soft tissue defects after removing malignant bone tumors have been described. Typically, a tumor prosthesis is employed for reconstruction following osteosarcoma removal. However, …

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Nanomaterial-Doped Xerogels for Biosensing Measurements of Xanthine in Clinical and Industrial Applications

Quang Minh Dang, Ann H. Wemple, Michael C. Leopold

First-generation amperometric xanthine (XAN) biosensors, assembled via layer-by-layer methodology and featuring xerogels doped with gold nanoparticles (Au-NPs), were the focus of this study and involved both fundamental exploration of the materials as well as demonstrated usage of the biosensor in both clinical …

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