J. Berkofsky

The Contribution of Alanine to Renal Ammoniagenesis: In vitro Studies in the Rat1

Guy Lemieux, Christiane Lemieux, Mireille Marsolais, A. Quenneville et autres

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Renal Ammoniagenesis by the Bullfrog Kidney. Effect of Acid Loading1

Guy Lemieux, J. Berkofsky, Christiane Lemieux, A. Quenneville et autres

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Metabolic characteristics of cat kidney: failure to adapt to metabolic acidosis

Guy Lemieux, Christiane Lemieux, S. Duplessis, J. Berkofsky

During studies performed on domestic cats made acidotic with ammonium chloride, it was found that the cat kidney is unable to adapt to metabolic acidosis. Renal proximal tubules do not increase their production of ammonia or glucose from glutamine during acidosis. During …

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Real importance of alanine in renal metabolism: in vitro studies in rat and dog

Guy Lemieux, J. Berkofsky, Christiane Lemieux, A. Quenneville et autres

In vitro studies were performed on cortical renal tubules to clarify possible differences between dog and rat with regard to alanine production and to define more precisely the role of alanine on ammonia and glucose production by the kidney. It was established …

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FAILURE OF THE KIDNEY TO OXIDIZE FATTY ACIDS DURING DIABETIC KETOACIDOSIS

Christiane Lemieux, J. Berkofsky, Guy Lemieux

A ROLE FOR ALANINE BIOSYNTHESIS BY THE KIDNEY

Guy Lemieux, J. Berkofsky, Christiane Lemieux, A. Quenneville et autres

Renal tissue metabolism in the rat during chronic metabolic alkalosis: importance of glycolysis

Guy Lemieux, J. Berkofsky, Christiane Lemieux

Chronic metabolic alkalosis was induced in rats drinking 0.3 M NaHCO3 and receiving 1 mg furosemide/100 g body weight per day intraperitoneally. Another group of animals received a potassium supplement in the form of 0.3 M KHCO3. In this group, hypokalemia did …

Net tubular secretion of bicarbonate by the alligator kidney. Antimammalian response to acetazolamide

Guy Lemieux, J. Berkofsky, A. Quenneville, Christiane Lemieux

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Metabolic machinery of the alligator kidney

Guy Lemieux, André G. Craan, A. Quenneville, Christiane Lemieux et autres

Crocodilians such as caimans and alligators are uricotelic and ammoniotelic animals. They are carnivorous but they excrete ammonium ions in an alkaline urine. The metabolic organization of the kidney of the Mississippi alligator was studied by measuring the renal metabolite profile, the …