Yongzhe Wang

Baseline gene expression and dynamic endocrine therapy use in ER+ breast cancer: associations with recurrence in a real-world cohort

Veronica Jones, Yongzhe Wang, Christine Quinones, Dana Aljaber et autres

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Racial differences in breast cancer-specific mortality and CVD-specific mortality after breast cancer in post-menopausal women

Kerryn W. Reding, Alexi Vasbinder, Richard K. Cheng, Ana Barac et autres

BACKGROUND: Racial disparities in all-cause mortality after breast cancer (BC) have been documented. While elevated risk of BC mortality experienced by Black women is clear, it is unclear the relative contribution of cardiovascular disease (CVD) mortality to the survival disparity in Black …

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Divergent prefrontal cortex circuits regulate cued food seeking under distinct metabolic or emotional states

Xu O. Zhang, Guillermo Aquino-Miranda, Claire E. Cho, Yongzhe Wang et autres

Flexibly adjusting food-seeking behaviour in response to food-associated cues and internal states is crucial for animals’ survival. However, the neural mechanisms that modulate cued food-seeking behaviour during varying metabolic (i.e., hungry vs. satiated) and emotional (i.e., safe vs. threatened) states remain elusive. …

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Impact of Travel Burden on Timeliness of Care and Overall Survival for Breast Cancer: A National Cancer Database Analysis

Yongzhe Wang, Christine M. Quinones, Elizabeth Gonzalez, Preeti Farmah et autres

INTRODUCTION: Timely treatment initiation is critical to clinical outcomes in breast cancer (BC). While social determinants of health are established drivers of disparities in the timeliness of care (ToC), the impact of travel burden remains less defined. This study evaluates associations between …

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“I probably shouldn’t go in today”: Inequitable access to paid sick leave and its impacts on health behaviors during the emergence of COVID-19 in the Seattle area

Chidozie Declan Iwu, Sarah N. Cox, Sarah L Sohlberg, Ashley Kim et autres

This study examines inequities in access to paid sick leave (PSL) by race/ethnicity, income, and sex and the role of PSL access on leave-taking and care-seeking behaviors among Seattle-area workers in the months leading up to and during the emergence of COVID-19 …

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Absenteeism and Health Behavior Trends Associated With Acute Respiratory Illness Before and During the COVID-19 Pandemic in a Community Household Cohort, King County, Washington

Erin Chung, Yongzhe Wang, Eric J. Chow, Anne Emanuels et autres

Introduction Longitudinal data on how acute respiratory illness (ARI) affects behavior, namely school or work participation, and nonpharmaceutical intervention (NPI) usage before and during the COVID-19 pandemic is limited. The authors assessed how ARIs and specific symptoms affected school, work, and health-related …

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Risk of Subsequent Respiratory Virus Detection After Primary Virus Detection in a Community Household Study—King County, Washington, 2019–2021

Jessica Heimonen, Eric J. Chow, Yongzhe Wang, James P. Hughes et autres

BACKGROUND: The epidemiology of respiratory viral infections is complex. How infection with one respiratory virus affects risk of subsequent infection with the same or another respiratory virus is not well described. METHODS: From October 2019 to June 2021, enrolled households completed active …

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Respiratory syncytial virus and other respiratory virus infections in residents of homeless shelters – King County, Washington, 2019–2021

Denise J. McCulloch, Julia H. Rogers, Yongzhe Wang, Eric J. Chow et autres

Respiratory syncytial virus (RSV) causes disproportionate morbidity and mortality in vulnerable populations. We tested residents of homeless shelters in Seattle, Washington for RSV in a repeated cross-sectional study as part of community surveillance for respiratory viruses. Of 15 364 specimens tested, 35 …

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1904. Health Behavioral Trends and Absenteeism Associated with Acute Respiratory Illness Before and During the SARS-CoV-2 Pandemic in a Community Household Cohort, King County, Washington

Erin Chung, Jessica Heimonen, Jessica O’Hanlon, Yongzhe Wang et autres

Abstract Background Non-pharmaceutical interventions (NPIs), such as masking and social distancing, can reduce SARS-CoV-2 transmission. Longitudinal behavioral data in individuals with acute respiratory illness (ARI) during the COVID-19 pandemic are limited. We describe changes in adherence to NPIs and the impact of …

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2202. Influenza Surveillance of Families in an Observational Household Study 2019-2021

Tara M Babu, Amanda M. Casto, Jessica Heimonen, Yongzhe Wang et autres

Abstract Background Families with children may be at higher risk for influenza infection. Community transmission can suffer from underreporting as testing is often not performed. We studied the epidemiology of influenza in households with school-aged children using home-based sample collection. Methods We …

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