Astrid Telhaug Karlsson

Cognitive function in long-term survivors after treatment for brain metastases compared with normative samples

Guro Lindviksmoen Astrup, Monica Kløvstad Siksjø, Nina Aass, Guido Werner Alves et autres

Abstract Background Few studies have examined cognitive function in long-term survivors with brain metastases (BM). The aim of this study was to assess performance-based cognitive function and compare it with normative samples. Methods Patients with ≥2-year survival after a first-time BM diagnosis …

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Patient-Reported Outcomes Before and After Radiotherapy for Brain Metastases—A Prospective Cohort Study of 239 Non-Small-Cell Lung Cancer Patients

Astrid Telhaug Karlsson, Marianne Jensen Hjermstad, Nina Aass, Eva Skovlund et autres

Introduction: Radiotherapy (RT) is a frequently offered treatment option for brain metastases (BMs) in patients with non-small-cell lung cancer (NSCLC). This study presents patient-reported outcomes (PROs) in a cohort of NSCLC with BMs treated with RT. This study researched how PRO scores …

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Survival and quality of life after first-time diagnosis of brain metastases: a multicenter, prospective, observational study

Olav Erich Yri, Guro Lindviksmoen Astrup, Astrid Telhaug Karlsson, René van Helvoirt et autres

Background: A major concern in anticancer treatment (ACT) of brain metastases (BM) is exposing patients with short expected survival to treatments that negatively impact on quality of life (QoL). Such futile ACT at the end of life is time-consuming and burdensome for …

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Overall Survival after Radiotherapy for Brain Metastases According to ECOG Status—A Prospective Study of 294 NSCLC Patients

Astrid Telhaug Karlsson, Marianne Jensen Hjermstad, Nina Aass, Eva Skovlund et autres

Up to 40% of non-smallcell lung cancer (NSCLC) patients develop brain metastases (BMs). The potential benefits of radiotherapy (RT) in patients with poor performance status (PS) are questionable, with considerable risk for futile treatment. We analyzed overall survival after initial radiotherapy in …

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Overall survival after initial radiotherapy for brain metastases; a population based study of 2140 patients with non-small cell lung cancer

Astrid Telhaug Karlsson, Marianne Jensen Hjermstad, Therese Omdahl, Nina Aass et autres

Background Brain metastases (BM) occur in about 30% of all patients with non-small cell lung cancer (NSCLC). BM treatment guidelines recommend more frequent use of stereotactic radiotherapy (SRT). Overall, studies report no difference in overall survival (OS) comparing SRT to whole-brain radiotherapy …

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Overall survival after initial radiotherapy for brain metastases; a population based study of 2140 patients with non-small cell lung cancer

Astrid Telhaug Karlsson, Marianne Jensen Hjermstad, Therese Omdahl, Nina Aass et autres

Brain metastases (BM) occur in about 30% of all patients with non-small cell lung cancer (NSCLC). BM treatment guidelines recommend more frequent use of stereotactic radiotherapy (SRT). Overall, studies report no difference in overall survival (OS) comparing SRT to whole-brain radiotherapy (WBRT). …