Accès ouvert
2026
article
OpenAlex
Francesco Ragonese, Andrea Biagini, Luana Sallicandro, Alessandra Mirarchi et autres
Abstract Silver nanoparticles (AgNPs) have emerged as a promising therapeutic tool for managing glioblastoma (GB), particularly in radiosensitisation. However, their mechanisms of action are not yet fully understood. Since ion channel activity is implicated in various aspects of radioresistance, we investigated the …
it
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Accès ouvert
2026
article
OpenAlex
Andrea Biagini, Luana Sallicandro, Jasmine Covarelli, Rosaria Gentile et autres
Skeletal muscle differentiation is tightly regulated by membrane potential dynamics and voltage-dependent ion channel activity. Potassium (K+) and calcium (Ca2+) currents cooperate to orchestrate the transition of myoblasts into fusion-competent myotubes, and alterations in this process are associated with dystrophic phenotypes. Here, …
it, al
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Accès ouvert
2026
article
OpenAlex
Simona Polakovičová, Ivan Varga, Barbora Filová, Luana Sallicandro et autres
BACKGROUND: Although Merkel cells (MCs) are well-established mechanoreceptors in human skin, their function within the vaginal epithelium remains undefined. The aim of the present histological study was to investigate whether MCs located in the stratified epithelium of the anterior wall of the …
sk, lv, it, cz
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Accès ouvert
2025
article
OpenAlex
Rosaria Gentile, Davide Feudi, Luana Sallicandro, Andrea Biagini
Neoplastic cells are characterized by metabolic reprogramming, known as the Warburg effect, in which glucose metabolism is predominantly directed toward aerobic glycolysis, with reduced mitochondrial oxidative phosphorylation and increased lactate production even in the presence of oxygen. This phenomenon provides cancer cells …
it
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Accès ouvert
2025
article
OpenAlex
Paola Sabbatini, Sabrina Cipriani, Andrea Biagini, Luana Sallicandro et autres
Amniotic fluid is a complex and dynamic biological matrix that surrounds the fetus during the pregnancy. From this fluid, is possible to isolate various cell types with particular interest directed towards stem cells (AF-SCs). These cells are highly appealing due to their …
it, al
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Accès ouvert
2024
article
OpenAlex
Diletta Del Bianco, Rosaria Gentile, Luana Sallicandro, Andrea Biagini et autres
Oocyte–cumulus cell interaction is essential for oocyte maturation and competence. The bidirectional crosstalk network mediated by gap junctions is fundamental for the metabolic cooperation between these cells. As cumulus cells exhibit a more glycolytic phenotype, they can provide metabolic substrates that the …
it, al
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Accès ouvert
2024
article
OpenAlex
Luana Sallicandro, Elko Gliozheni, Davide Feudi, Paola Sabbatini et autres
Introduction: Polycystic ovary syndrome (PCOS) is a common multifactorial and polygenic disorder of the endocrine system, affecting up to 20% of women in reproductive age with a still unknown etiology. Follicular fluid (FF) represents an environment for the normal development of follicles …
it
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Accès ouvert
2023
article
OpenAlex
Alessandro Zucchi, Francesco Claps, Antonio Luigi Pastore, Alessandro Perotti et autres
Bladder cancer is the most common tumor of the urinary system, with a high incidence in the male population. Surgery and intravesical instillations can eradicate it, although recurrences are very common, with possible progression. For this reason, adjuvant therapy should be considered …
it
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