Ana Hidalgo-Conde

Risk loci involved in giant cell arteritis susceptibility: a genome-wide association study

Gonzalo Borrego‐Yaniz, Lourdes Ortiz‐Fernández, Adela Madrid-Paredes, Martin Kerick et autres

Background Giant cell arteritis is an age-related vasculitis that mainly affects the aorta and its branches in individuals aged 50 years and older. Current options for diagnosis and treatment are scarce, highlighting the need to better understand its underlying pathogenesis. Genome-wide association …

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Rate of severe and fatal infections in a cohort of patients with interstitial lung disease associated with rheumatoid arthritis: a multicenter prospective study

Natalia Mena‐Vázquez, Roció Redondo‐Rodríguez, M. Rojas-Giménez, Carmen María Romero-Barco et autres

Objective To describe severe infection, foci of infection, microorganisms, associated factors, and impact on mortality in patients with rheumatoid arthritis–associated interstitial lung disease (RA-ILD). Patients and methods The study was based on a multicenter prospective cohort of patients with RA-ILD followed up …

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Protocolo diagnóstico y cuantificación de los factores de riesgo cardiovascular en pacientes con enfermedades autoinmunes sistémicas y con infección por el VIH

Guillermo Ojeda, Rocío Arnedo Díez de los Ríos, Ana Hidalgo-Conde

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Correction: Corrigendum: Analysis of the common genetic component of large-vessel vasculitides through a meta-Immunochip strategy

F. David Carmona, Patrick Coit, Güher Saruhan‐Direskeneli, José Hernández‐Rodríguez et autres

Scientific Reports 7: Article number: 43953; published online: 09 March 2017; updated: 05 April 2017 In this Article, Javier Martin is incorrectly listed as being affiliated with “Departamento de Genética e Instituto de Biotecnología, Universidad de Granada, Granada 18016, Spain”. The correct …

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Analysis of the common genetic component of large-vessel vasculitides through a meta-Immunochip strategy

F. David Carmona, Patrick Coit, Güher Saruhan‐Direskeneli, José Hernández‐Rodríguez et autres

Abstract Giant cell arteritis (GCA) and Takayasu’s arteritis (TAK) are major forms of large-vessel vasculitis (LVV) that share clinical features. To evaluate their genetic similarities, we analysed Immunochip genotyping data from 1,434 LVV patients and 3,814 unaffected controls. Genetic pleiotropy was also …

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A Genome-wide Association Study Identifies Risk Alleles in Plasminogen and P4HA2 Associated with Giant Cell Arteritis

F. David Carmona, Augusto Vaglio, Sarah Mackie, José Hernández‐Rodríguez et autres

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A Large-Scale Genetic Analysis Reveals a Strong Contribution of the HLA Class II Region to Giant Cell Arteritis Susceptibility

F. David Carmona, Sarah Mackie, Jose‐Ezequiel Martín, John Taylor et autres

We conducted a large-scale genetic analysis on giant cell arteritis (GCA), a polygenic immune-mediated vasculitis. A case-control cohort, comprising 1,651 case subjects with GCA and 15,306 unrelated control subjects from six different countries of European ancestry, was genotyped by the Immunochip array. …

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Analysis of two autoimmunity genes, IRAK1 and MECP2, in giant cell arteritis.

Ana Márquez, Roser Solans, José Hernández‐Rodríguez, Cid Mc et autres

OBJECTIVES: The Xq28 region, containing IRAK and MECP2, represent a common susceptibility locus for a high number of autoimmune diseases. Our aim in the present study was to evaluate the influence of the IRAK1 and MECP2 autoimmunity-associated genetic variants in the giant …

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Incidence of Cancer in a Cohort of Spanish Patients With Systemic Lupus Erythematosus

Ana Hidalgo-Conde, Manuel de Haro Liger, Manuel Abarca-Costalago, Martina Álvarez Pérez et autres

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Incidence of Cancer in a Cohort of Spanish Patients With Systemic Lupus Erythematosus

Ana Hidalgo-Conde, Manuel de Haro Liger, Manuel Abarca-Costalago, Martina Álvarez Pérez et autres

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Role of an intermittent claudication questionnaire for the diagnosis of PAD in ambulatory patients with type 2 diabetes.

José Mancera‐Romero, A. Rodríguez-Morata, Miguel Ángel Sánchez-Chaparro, M.R. Sánchez-Pérez et autres

AIM: In epidemiological studies, peripheral arterial disease is assessed by the measurement of the ankle/brachial index (ABI), thus enabling detection of asymptomatic disease. Our aim was to evaluate the diagnostic accuracy of a validated questionnaire on intermittent claudication for peripheral arterial disease …

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A case-control study suggests that the CCR6 locus is not involved in the susceptibility to giant cell arteritis.

Aurora Serrano, F. David Carmona, Santos Castañeda, Miranda-Filloy Ja et autres

OBJECTIVES: Polymorphisms of the CC chemokine receptor 6 (CCR6) gene have been recently reported to be associated with a number of autoimmune diseases. We aimed to investigate the possible influence of CCR6 rs3093024 gene variant in the susceptibility to and clinical expression …

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