Charlotte B. Mathisen

A novel diagnostic serum protein signature for pediatric inflammatory bowel disease

Charlotte B. Mathisen, Niklas Nyström, Igor Bazov, Ove Øyås et autres

OBJECTIVES: Diagnostic delay is common in pediatric inflammatory bowel disease (PIBD), and fecal calprotectin (FCP) is often limited by challenges with sample collection. Therefore, we aimed to identify and validate a blood-based diagnostic protein signature of PIBD. METHODS: Proteins were analyzed using …

no, se, es (code pays fourni par la source)

P0088 The exposome metabolome in paediatric inflammatory bowel disease: A cross-sectional study in a population-based Norwegian cohort

Benita Salomon, Samira Salihovic, Charlotte B. Mathisen, Svend Andersen et autres

Abstract Background Paediatric inflammatory bowel disease (IBD), comprising the subtypes Crohn’s disease (CD) and ulcerative colitis (UC), is believed to result from an interplay between genetic predisposition and environmental exposures. Examining exposome metabolome may help to identify environmental exposures, including host-derived metabolites, …

se, no, fi (code pays fourni par la source)

Identification and validation of a blood- based diagnostic lipidomic signature of pediatric inflammatory bowel disease

Samira Salihović, Niklas Nyström, Charlotte B. Mathisen, Robert Kruse et autres

Improved biomarkers are needed for pediatric inflammatory bowel disease. Here we identify a diagnostic lipidomic signature for pediatric inflammatory bowel disease by analyzing blood samples from a discovery cohort of incident treatment-naïve pediatric patients and validating findings in an independent inception cohort. …

se, no, gb, dk, es, it, fi (code pays fourni par la source)

Su1759 IDENTIFICATION AND VALIDATION OF A LIPIDOMIC SIGNATURE AS A NOVEL DIAGNOSTIC BIOMARKER OF PEDIATRIC INFLAMMATORY BOWEL DISEASE

Samira Salihović, Niklas Nyström, Charlotte B. Mathisen, Svend Andersen et autres

Su1758 A NOVEL SERUM PROTEIN SIGNATURE AS BIOMARKER FOR INFLAMMATORY BOWEL DISEASE: A DIAGNOSTIC PERFORMANCE AND PREDICTION MODELLING STUDY USING DATA FROM TWO INDEPENDENT INCEPTION COHORTS

Igor Bazov, Robert L. Kruse, Daniel Bergemalm, Carl Eriksson et autres

Su1757 A NOVEL DIAGNOSTIC SERUM PROTEIN SIGNATURE FOR PEDIATRIC INFLAMMATORY BOWEL DISEASE: A DISCOVERY AND VALIDATION STUDY IN TWO INDEPENDENT INCEPTION COHORTS

Charlotte B. Mathisen, Igor Bazov, Niklas Nyström, Svend Andersen et autres

P154 A novel serum protein signature as biomarker for Inflammatory Bowel Disease: A diagnostic performance and prediction modelling study using data from two independent inception cohorts

I Bazov, Robert L. Kruse, Daniel Bergemalm, Carl Eriksson et autres

Abstract Background The diagnosis of inflammatory bowel disease (IBD) is often delayed since existing biomarkers in blood are imprecise and faecal tests are poorly accepted by patients. Therefore, we aimed to identify a diagnostic serum protein signature and validate its performance and …

se, no, es (code pays fourni par la source)

DOP14 Identification and validation of a lipidomic signature as a novel diagnostic biomarker of paediatric Inflammatory Bowel Disease

Selma Salihovic, Niklas Nyström, Charlotte B. Mathisen, Svend Andersen et autres

Abstract Background Improved diagnostic biomarkers are an unmet clinical need for paediatric inflammatory bowel disease (IBD). We therefore aimed to identify a diagnostic lipidomic signature of IBD in blood. Methods We performed a non-targeted liquid chromatography-time of flight mass spectrometry-based lipidomics (UPLC-QTOFMS) …

se, no (code pays fourni par la source)

DOP11 A novel diagnostic serum protein signature for paediatric Inflammatory Bowel Disease: A discovery and validation study in two independent inception cohorts

Charlotte B. Mathisen, Niklas Nyström, I Bazov, Svend Andersen et autres

Abstract Background A diagnostic delay is common in paediatric inflammatory bowel disease (PIBD) and is associated with impaired outcomes. Therefore, we aimed to identify and validate a diagnostic protein signature of PIBD in blood. Methods Using the Proximity Extension Assay technology (Olink …

no, se, es (code pays fourni par la source)