Emilio Freixas

Disodium pamidronate for treating severe hypercalcemia in a hemodialysis patient

Hernán Trimarchi, Fernando Lombi, Mariano Forrester, Cristina María Elizondo et autres

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Subject Index Vol. 102, 2006

Sungdo Kim, Byoung-Soo Cho, Maria Koukoulaki, David R.W. Jayne et autres

c61 Hypertension c43 Hypoalbuminemia c115 IgA c81 Immunoglobulin G c122 -M c122 Innate immunity c93 Interleukin-8 c51 Interstitial fi brosis c133 Intima-media thickness c14 Intravenous c88 -immunoglobulin c35 -maxacalcitol therapy c1 Lanthanum carbonate c61 Macrophage colony-stimulating factor c14 Mannose

Clopidogrel Diminishes Hemodialysis Access Graft Thrombosis

Hernán Trimarchi, Pablo Young, Mariano Forrester, Juan Schropp et autres

BACKGROUND: The most common complication of hemodialysis (HD) access graft is thrombosis. Clopidogrel, an inhibitor of platelet aggregation, was assessed to prevent this serious complication. METHODS: A prospective study in which 24 patients on chronic HD whose vascular accesses were grafts were …

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[Hyperhomocysteinemia as a vascular risk factor in chronic hemodialysis patients].

Hernán Trimarchi, Pablo Young, María L Díaz, Juan Schropp et autres

Homocysteine is an independent risk factor for cardiovascular disease in the general population. In addition, it plays a main role in the development of atherogenesis and thrombosis, particularly in end-stage renal disease patients. Therefore, hemodialysis patients are under the burden of homocysteine …

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Clopidogrel Diminishes Hemodialysis access Graft Thrombosis

Hernán Trimarchi, Pablo Young, Mariano Forrester, Juan Schropp et autres

BACKGROUND: The most common complication of hemodialysis access graft is thrombosis. Clopidogrel, an inhibitor of platelet aggregation, was assessed to prevent this serious complication. METHODS: Nineteen patients on chronic hemodialysis whose vascular accesses were grafts were divided into two groups: Group A …

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La n-acetilcisteína disminuye los niveles de malondialdehido plasmático en los pacientes en hemodiálisis crónica. Impacto sobre el estrés oxidativo. Un esstudio piloto

Hernán Trimarchi, Mariano Forrester, Juan Schropp, Horacio Pereyra et autres

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Thrombotic Events of Arteriovenous Fistulae in Hemodialysis Patients Related to the C677T Thermolabile Variant of Methylenetetrahydrofolate Reductase

Hernán Trimarchi, Valeria Genoud, Juan Schropp, María Mercedes Castañón et autres

BACKGROUND: Hyperhomocysteinemia is a risk factor for thrombosis, a frequent complication of vascular access (VA) in hemodialysis (HD). The enzyme methylenetetrahydrofolate reductase (MTHFR) is necessary for the remethylation of homocysteine (Hcy) to methionine. It has been postulated that patients homozygous and, to …

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Low Initial Vitamin B12 Levels in Helicobacter pylori-Positive Patients on Chronic Hemodialysis

Hernán Trimarchi, Mariano Forrester, Juan Schropp, Horacio Pereyra et autres

BACKGROUND: Helicobacter pylori has been identified as a possible cause of vitamin B12 deficiency in the general population. We assessed any potential relationship between low cyanocobalamin serum levels and Helicobacter pylori status in hemodialysis patients and subsequently correlated these results with the …

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N-acetylcysteine reduces malondialdehyde levels in chronic hemodialysis patients - a pilot study

Hernán Trimarchi, Martina Mongitore, Pablo Baglioni, Matthew D. Forrester et autres

BACKGROUND: Oxidative stress has been implicated in the development of endothelial damage in hemodialysis (HD). We have assessed the effects of N-acetylcysteine (NAC), a compound with antioxidant effects, on malondialdehyde (MDA), a marker of oxidative stress on lipid peroxidation. METHODS: A clinical …

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Late-Onset Cytomegalovirus-Associated Interstitial Nephritis in a Kidney Transplant

Hernán Trimarchi, Rosana Jordán, Alejandro Iotti, Mariano Forrester et autres

Cytomegalovirus is the most important viral infection in kidney transplants, but rarely affects the allograft after the sixth month posttransplantation. We present a patient who developed renal failure eighteen months posttransplant; a kidney biopsy showed cytomegalovirus inclusions, acute tubular necrosis and mild …

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Randomized Trial of Methylcobalamin and Folate Effects on Homocysteine in Hemodialysis Patients

Hernán Trimarchi, Amalia Schiel, Emilio Freixas, Marisa Díaz

BACKGROUND: There are no data available on the effects of intravenous (i.v.) methylcobalamin (Me-Cbl), the coenzymatically active form of vitamin B12 that acts as a cofactor for methionine synthase in the conversion of total homocysteine (tHcy) to methionine, with or without oral …

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The C677T thermolabile variant of methylene tetrahydrofolate reductase on homocysteine, folate and vitamin B12 in a hemodialysis center.

Hernán Trimarchi, Valeria Genoud, Amalia Schiel, María Mercedes Castañón et autres

Homocysteine is a risk factor for cardiovascular disease. Mutations in a key enzyme in homocysteine metabolism, methylenetetrahydrofolate reductase, may contribute to hyperhomocysteinemia and alter folate and cobalamin levels. After starting hemodialysis, 10 mg oral folate daily and 500 micrograms intravenous methylcobalamin once …

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