Accès ouvert
2024
article
OpenAlex
Stephen J. Balevic, Daniel K. Benjamin, William G. Powderly, P. Brian Smith et autres
Importance: The pharmacokinetics of abatacept and the association between abatacept exposure and outcomes in patients with severe COVID-19 are unknown. Objective: To characterize abatacept pharmacokinetics, relate drug exposure with clinical outcomes, and evaluate the need for dosage adjustments. Design, Setting, and Participants: …
us, fr
(code pays fourni par la source)
Accès ouvert
2023
article
OpenAlex
Jane A. O’Halloran, Emily R. Ko, Kevin Joseph Anstrom, Eyal Kedar et autres
Importance: Immune dysregulation contributes to poorer outcomes in COVID-19. Objective: To investigate whether abatacept, cenicriviroc, or infliximab provides benefit when added to standard care for COVID-19 pneumonia. Design, Setting, and Participants: Randomized, double-masked, placebo-controlled clinical trial using a master protocol to investigate …
us, ar, pe, mx, br, nl, fr
(code pays fourni par la source)
2022
article
OpenAlex
Crystal Honold, Brandi Anderson, Andrea Loggini, Jonatan Hornik et autres
To describe the treatment challenges related to multiple sclerosis (MS) relapse in the setting of cryptococcal meningitis.
us, in
(code pays fourni par la source)
Accès ouvert
2021
article
OpenAlex
Abdelhameed Nawwar, Julieta Madrid-Morales, Carolina Vélez-Mejía, Rigoberto De Jesus Pizarro et autres
Abstract Background Non-Tuberculous Mycobacteria (NTM) cause infections in immunocompetent as well as immunocompromised individuals affecting pulmonary and extra pulmonary sites. These pathogens are widely distributed globally and recent reports have shown their rise in many developed countries. Our study aimed to assess …
us
(code pays fourni par la source)
Accès ouvert
2017
article
OpenAlex
Ahmed M. Dirweesh, Afolarin Amodu, Muhammad Anees Khan, Ritika Zijoo et autres
Background: The prevalence of diverticulosis is increasing with 5-10% of patients developing diverticulitis and 5-15% developing symptomatic bleeding. Diverticulitis can result in abscess, perforation, fistula, or obstruction. Bleeding has combined morbidity and mortality rates of 10-20%. The purpose of this study was …
us
(code pays fourni par la source)