Prospects for Induced Pluripotent Stem Cell Therapy for Diabetes

Résumé fourni par la source

Although diabetes can be managed clinically with the use of insulin injections, it remains an incurable and inconvenient disorder. In the long term it is associated with a number of clinical complications, and there is a desire to see new methodologies to replace defective cells and provide a lasting normality without the need for drug treatment. Pluripotent stem cells offer the potential to generate any cell of the body as a source of cells for cellular therapeutic approaches. There remain many issues, however, that must be addressed before this type of treatment could become a reality. Induced pluripotent stem (iPS) cells offer a possibility of circumventing the ethical and immunologic response issues associated with the use of embryonic stem cells. There is, however, a need for a greater understanding of the underlying biology of diabetes and iPS cells for this form of therapy to become a reality.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.