An Integrative Feedback Model of Schizophrenia

Résumé fourni par la source

This paper presents a cross-disciplinary model, integrating the major findings of the past 40 years, to develop a more comprehensive view of the etiology and development of schizophrenia. A Literature Review is presented to expand on research covering each of the variables of the model, including genetic, neurological, and environmental. The model presented is a conceptual model intended to depict the relationship of various variables that place individuals at risk or protect them from developing schizophrenia. The model utilizes the concept of a feedback loop, which articulates the need to conceptualize the development of the disorder as being in a continuous state of interaction with all relevant variables. Consistent with this continuous interaction, this model assumes schizophrenia develops through multiple pathways. This is critical to an understanding of a disorder like schizophrenia that does not always have a pure genetic, neurological, or environmental source of causation. This model is intended as a conceptual tool to develop testable hypotheses for the purpose of developing potentially valuable solutions, such as early intervention programs.

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