Acute flaccid paralysis with anterior myelitis - California, June 2012-June 2014.
Rattachement africain : us. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
In August 2012, the California Department of Public Health (CDPH) was contacted by a San Francisco Bay area clinician who requested poliovirus testing for an unvaccinated man aged 29 years with acute flaccid paralysis (AFP) associated with anterior myelitis (i.e., evidence of inflammation of the spinal cord involving the grey matter including anterior horn cell bodies) and no history of international travel during the month before symptom onset. Within 2 weeks, CDPH had received reports of two additional cases of AFP with anterior myelitis of unknown etiology. Testing at CDPH's Viral and Rickettsial Disease Laboratory for stool, nasopharyngeal swab, and cerebrospinal fluid (CSF) did not detect the presence of an enterovirus (EV), the genus of the family Picornaviridae that includes poliovirus. Additional laboratory testing for infectious diseases conducted at the CDPH Viral and Rickettsial Disease Laboratory did not identify a causative agent to explain the observed clinical syndrome reported among the patients. To identify other cases of AFP with anterior myelitis and elucidate possible common etiologies, CDPH posted alerts in official communications for California local health departments during December 2012, July 2013, and February 2014. Reports of cases of neurologic illness received by CDPH were investigated throughout this period, and clinicians were encouraged to submit clinical samples for testing. A total of 23 cases of AFP with anterior myelitis of unknown etiology were identified. Epidemiologic and laboratory investigation did not identify poliovirus infection as a possible cause for the observed cases. No common etiology was identified to explain the reported cases, although EV-D68 was identified in upper respiratory tract specimens of two patients. EV infection, including poliovirus infection, should be considered in the differential diagnosis in cases of AFP with anterior myelitis and testing performed per CDC guidelines.
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California Department of Public Health pays non établi dans la noticeOrganisme public
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Lucile Packard Children's Hospital pays non établi dans la noticeÉtablissement de santé
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Stanford University pays non établi dans la noticeUniversité ou école supérieure
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University of California pays non établi dans la noticeUniversité ou école supérieure
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Centers for Disease Control and Prevention pays non établi dans la noticeInstitution
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Lucille Packard Children’s Hospital pays non établi dans la noticeÉtablissement de santé
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California Dept. of Public Health pays non établi dans la noticeInstitution
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Centers for Disease Control & Prevention pays non établi dans la noticeInstitution
California Department of Public Health, Lucile Packard Children's Hospital et Stanford University, avec 5 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.