Structure–function coupling reveals hemisphere-specific network reorganization after stroke

Le résumé fourni par la source

Longitudinal multimodal MRI-derived structure–function coupling (SFC) data and analysis code from mouse models of experimental stroke. The resource integrates resting-state functional connectivity (FC) derived from rs-fMRI with structural connectivity (SC) derived from diffusion MRI to quantify regional FC–SC coupling in the sensorimotor network (SMN) and default mode network (DMN). Two stroke models are included: photothrombotic stroke (PT), producing predominantly cortical lesions, and middle cerebral artery occlusion (MCAO), producing cortico-striatal lesions. Longitudinal measurements cover baseline and weeks 1, 2, and 4 post-stroke. MATLAB scripts are provided for SFC calculation, R scripts for statistical analysis, and Python scripts for replotting regional SFC results on a three-view mouse brain atlas for improved anatomical visualization.

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