Pancreatic adenocarcinoma treated with MEK, autophagy and immune checkpoint inhibitors reveals a responsive epithelial subtype within the heterogenous tumor that is enriched in murine models but not in humans
Le résumé fourni par la source
Single-Nucleus RNA-Seq Data from Pancreatic Cancer patients on clinical trial. Includes integrated gene expression seurat object with raw counts and scaled data as well as metadata annotations for each cell. Also includes integrated VIPER inferred protein activity object with metadata labels, and R script with code for survival analyses, frequency plots, and GSEA enrichment analyses. See manuscript methods for further detail.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.