Microbial Carbon Capture in Precision Fermentation

Le résumé fourni par la source

The development of precision fermentation has unlocked new frontiers in industrial biotechnology, offering a platform for producing specific biomolecules using controlled microbial processes. A promising extension of this technology is the integration of microbial carbon capture (MCC), which allows the direct utilization of carbon dioxide (CO₂) during fermentation. Specific microorganisms, including Cupriavidusnecator and Ralstoniaeutropha , naturally possess carbon fixation capabilities and are utilized to convert CO₂ into bio-based materials such as polyhydroxyalkanoates (PHAs). In parallel, synthetic biology approaches have engineered conventional fermentation hosts like Escherichia coli and Saccharomyces cerevisiae to incorporate CO₂ assimilation pathways, expanding their metabolic potential. Photosynthetic microbes such as Synechococcus elongatus and microalgae like Chlamydomonas reinhardtii are also being connected for the invention of biofuels, organic acids, and therapeutic compounds, while simultaneously reducing atmospheric CO₂ levels. This present study examines the use of carbon-fixing microbes in precision fermentation, highlighting strategies for strain development, process optimization, and the broader environmental impact. By coupling biomanufacturing with carbon mitigation, microbial carbon capture signifies a pivotal step toward a more sustainable and circular bioeconomy.

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