MOESM10 of The cohesin-associated protein Wapal is required for proper Polycomb-mediated gene silencing

Le résumé fourni par la source

Additional file 10: Figure S8. A) Log2 fold change in expression of six Polycomb-marked genes derepressed after Wapal depletion with two different shRNAs. Color scheme shown to right. B) IGV screen captures of two loci (Snai2 and Ppp1r3c) in which a combined Wapal-/CTCF-binding site is >2kb from the TSS, but also illustrates increased binding of Wapal around the TSS. Other aspects are similar to Figure S3.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.