Additional file 2 of Leptin attenuates heat stress-induced mitoxyperilysis in porcine Sertoli cells by suppressing the mtDNA-cGAS-STING axis

Résumé fourni par la source

Additional file 2: Text S1. Sertoli cell collection. Text S2. Mitochondrial function assays. Text S3. Mitochondrial DNA stress response assay. Fig. S1. Purity analysis of primary Sertoli cells. Fig. S2. Inhibition of BAX/BAK or VDAC1 oligomerization blocks heat stress-induced mtDNA release and subsequent cGAS-STING pathway activation. Fig. S3. Leptin inhibits heat stress-induced p65 activation in Sertoli cells.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.