Atlas-scale single-cell analysis beyond in-memory paradigm with scAtlasPy

Le résumé fourni par la source

A scalable Python platform for atlas-scale single-cell omics analysis beyond in-memory limits.scAtlasPy is a Python platform for analyzing cell atlases that are too large to fit in memory. It extends familiar single-cell analysis workflows to atlas-scale datasets, supporting preprocessing, dimensionality reduction, clustering, visualization, marker analysis, and machine learning within a unified on-disk environment.At the center of scAtlasPy is a persistent .sasql atlas database. Expression matrices, metadata, embeddings, and analysis results remain on disk, while analysis functions retrieve only the cells, genes, or minibatches needed for the current operation.

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