Seroprevalence of viral hemorrhagic fevers and arboviral infections among febrile patients in Forest Guinea

Résumé fourni par la source

Between 2017 and 2024, routine diagnostics surveillance in Guinea detected several confirmed viral hemorrhagic fever (VHF) cases among febrile patients. To assess exposure to Lassa virus and other viral pathogens, we conducted a retrospective cross-sectional seroprevalence study in Forest Guinea (Guéckédou and N′Zérékoré). Lassa virus seroprevalence was 56.0% in the Guéckédou study group and 29.8% in the N′Zérékoré study group. Seropositivity increased with age in both study groups, suggesting cumulative exposure. Samples from Guéckédou laboratory were also tested for other pathogens, and antibodies against Marburg virus (5.8%), Zika virus (5.4%) and Crimean-Congo haemorrhagic fever virus (1.2%) were detected.