BRONCHIAL INFLAMMATION IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE: RELATIONSHIP WITH EMPHYSEMA AND SMALL AIRWAYS DISEASE

Résumé fourni par la source

Chronic obstructive pulmonary disease (COPD) is a chronic-progressive disease with high prevalence characterized by progressive chronic airflow limitation not fully reversible, its classifications is based on spirometric values and symptoms. Cigarette smoking represents the most important risk factor for the development of COPD. Pathological studies show inflammation in lungs of patients with COPD. The inflammation in the lungs can lead to different pathological alterations and this to a different subtypes of disease: A) Chronic bronchitis, B) Emphysema, C) small airways disease. Current pathogenetic hypothesis for COPD explains chronic airflow limitation with an abnormal inflammatory response to particles and inhaled gases. Radiological tests like High resolution Computerized Tomography can give macroscopic information about lung parenchyma and airways morphology and moreover can estimate the subtype of COPD.

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