Association between Muscle Strength and Cardiovascular Disease Risk across Glycemic Status Groups: A Prospective Nationwide Cohort Study.

Le résumé fourni par la source

Objective: We aimed to investigate the independent and combined associations of grip strength and chair-rising time with cardiovascular disease (CVD) risk among middle-aged and older adults across different glycemic status groups. Methods: This study included 7,258 CVD-free middle-aged and older adults from the China Health and Retirement Longitudinal Study (CHARLS). Muscle strength was assessed based on grip strength and chair-rising time. Incident CVD was defined as a physician-diagnosed heart disease and/or stroke. Cox proportional hazard models and restricted cubic spline analyses were used to quantify the association between muscle strength and CVD. Results: for interaction = 0.622). Conclusion: This study revealed a dose-dependent association between muscle strength and the incidence of CVD. The associations between lower grip strength and prolonged chair-rising time with higher CVD risk were directionally consistent across the glycemic status groups, although not all strata reached statistical significance.

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