Deferred cord clamping during term/late preterm cesarean section under general and regional anesthesia: a retrospective study

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OBJECTIVE: To investigate the effects of anesthesia type and deferred umbilical cord clamping (DCC) on short-term maternal and neonatal outcomes at Cesarean section (CS). METHODS: This single-center retrospective study of all CS ≥35 weeks from January 2018-December 2023 compared maternal and neonatal outcomes between deliveries with and without DCC ≥60 seconds (s) under general anesthesia (GA) versus regional anesthesia (RA). The cord was clamped earlier for maternal hemorrhage, placental separation, cord avulsion, or infant apnea after 30-60s. Multivariable generalized estimating equations were used to assess the independent and joint effects of anesthesia type and DCC on outcomes, adjusting for emergent CS, chorioamnionitis, and severe preeclampsia/eclampsia. RESULTS: <.001). CONCLUSION: Regardless of anesthesia type, DCC ≥60s was not associated with higher risks of PPH or transfusion among mothers; and was not associated with any detriment in short term neonatal outcomes. We suggest that GA deliveries can be safely considered eligible for DCC under a standardized institutional protocol with predefined exit criteria.