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Additional file 4 of Cluster of 19 cases of eosinophilic meningitis due to Angiostrongylus cantonensis in Lifou, New Caledonia: an outbreak investigation

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Supplementary material 4: Figure S1A: Clinical presentation of cases. Symptoms are not mutually exclusive. Cervical pain was reported in three patients, including one presenting with meningeal syndrome. Vomiting was reported in nine patients. Figure S1B: Distribution of symptom onset following presumed exposure. Abbreviations: sp = evocative symptoms; sero = positive serology for Angiostrongylus cantonensis; Eo = blood eosinophilia.Case classification was defined according to international consensus criteria: confirmed cases required a positive cerebrospinal fluidPCR; probable cases met clinical criteria with CSF eosinophilia and supporting evidence; suspected cases were classified based on the number of minor criteria. The majority of cases occurred between weeks 2 and 4, with a peak at week 3, consistent with the expected incubation period of angiostrongyliasis. Figure S1C: Serological response to Angiostrongylus cantonensis among symptomatic and asymptomatic individuals. Serological results among symptomatic and exposed asymptomatic individuals. Black bars represent positive results and white bars represent negative results. Numbers within bars indicate counts. Figure S1D: Serological results for Toxocara spp. and Strongyloides spp. among all tested individuals. Serological results for Toxocara spp. and Strongyloides spp. are presented for all individuals tested; brown indicates positive results and white indicates negative results.

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