Haematological indices as markers of neuropathic pain in Nigerian cancer patients: a cross-sectional study
Rattachement africain : Nigéria. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Aim: Neuropathic pain (NP) is common in cancer patients, but its relationship with haematological inflammatory markers remains poorly understood. This study explored the association between NP and haematological parameters in Nigerian cancer patients. Methods: This cross-sectional study enrolled 90 patients with solid tumours from the University of Ilorin Teaching Hospital. Pain severity was assessed using the Numerical Rating Scale, while NP was evaluated with the painDETECT questionnaire. Complete blood count parameters were analysed, and derived inflammatory indices were calculated. Statistical analyses employed chi-square tests, Spearman’s correlation, and binary logistic regression. Results: NP was present in 21.1% of patients. Significant associations with NP were observed for haemoglobin (p = 0.006), absolute lymphocyte count (p = 0.003), platelet-to-lymphocyte ratio (PLR, p = 0.015), haemoglobin-to-platelet ratio (HPR, p = 0.001), and systemic immune-inflammation index (SII, p < 0.001). Correlation analysis showed NP positively correlated with platelet count (ρ = 0.23, p = 0.029), absolute neutrophil count (ρ = 0.263, p = 0.012), neutrophil-to-lymphocyte ratio (NLR, ρ = 0.248, p = 0.019), SII (ρ = 0.215, p = 0.045), and neutrophil-platelet score (NPS, ρ = 0.248, p = 0.018), while correlating negatively with haemoglobin (ρ = –0.223, p = 0.034). Logistic regression identified haemoglobin, platelet count, absolute lymphocyte count, absolute neutrophil count, NLR, and HPR as independent predictors of NP. Conclusions: Haematological parameters reflecting systemic inflammation are significantly associated with NP in cancer patients. These readily available indices may serve as useful adjuncts for identifying at-risk patients, particularly in resource-limited settings. Prospective studies are warranted to validate these findings.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Haematological indices as markers of neuropathic pain in Nigerian cancer patients: a cross-sectional study
- Date Crossref
- 31/08/2026
- Éditeur
- Open Exploration Publishing
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Ladoke Akintola University of Technology Nigéria (code pays fourni par la source)Université ou école supérieure
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University of Ilorin Teaching Hospital Department of Surgery University of Ilorin Teaching Hospital, Nigéria (code pays fourni par la source)Établissement de santé
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Ladoke Akintola University of Technology Teaching Hospital Nigéria (code pays fourni par la source)Établissement de santé
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LAUTECH Teaching Hospital Department of Haematology and Blood Transfusion Ogbomoso, Nigéria (pays nommé en fin d’affiliation)Établissement de santé
Ladoke Akintola University of Technology (Nigéria), Department of Surgery — University of Ilorin Teaching Hospital (University of Ilorin Teaching Hospital, Nigéria) et Ladoke Akintola University of Technology Teaching Hospital (Nigéria), avec 1 autre affiliation. Pays d’affiliation : Nigéria.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.