Health promoting spirulina platensis nanoparticles induce early embryonic loss in heat-stressed rabbit does
Rattachement africain : Égypte, tw. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Heat stress poses a major constraint to rabbit production by impairing reproductive performance, compromising embryo survival, and increasing oxidative stress. Spirulina, known for its rich content of proteins, antioxidants, and bioactive compounds, has been proposed as a natural dietary supplement to mitigate these detrimental effects. The present study aimed to prepare nano size spirulina to evaluate its impact on reproductive performance and embryo survival of New Zealand White rabbit does under heat stress conditions. Sixty healthy pluriparous does were allocated into four groups: control (G1), heat stress (G2), and two heat-stressed groups (G3 and G4) supplemented with spirulina nanoparticles at two different levels. Reproductive traits, hormonal profiles, oxidative stress markers, proinflammatory cytokines and histopathological changes were assessed. The results revealed that heat stress significantly reduced fertility rates, progesterone levels, and increased embryonic loss, accompanied by oxidative damage and inflammatory responses. Supplementation with spirulina nanoparticles improved the general health condition of mothers and alleviated the adverse effects of heat stress; elevated antioxidant capacity, number of oocytes, conception and implantation. However, spirulina nanoparticle supplementation also exerted immunomodulatory effects that were associated with inadequate development of the placental spiral arteries and increased early embryonic loss in the treated groups. These findings suggest that spirulina nanoparticles may offer protective benefits against heat stress in rabbits, but caution was advised regarding using nanoparticles for does kept for breeding.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Health promoting spirulina platensis nanoparticles induce early embryonic loss in heat-stressed rabbit does
- Date Crossref
- 26/08/2026
- Éditeur
- Springer Science and Business Media LLC
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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National Research Centre Department of Animal Reproduction and A.I Giza, Égypte (code pays fourni par la source)Structure de recherche
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Al-Azhar University Égypte (code pays fourni par la source)Université ou école supérieure
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Animal Health Research Institute pays non établi dans la noticeOrganisme public
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Cairo University Cairo University, Égypte (code pays fourni par la source)Université ou école supérieure
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Faculty of Agriculture Department of animal production Cairo, Égypte (pays nommé en fin d’affiliation)Université ou école supérieure
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Veterinary Research Institute Department of Animal Reproduction and A.I Giza, Égypte (pays nommé en fin d’affiliation)Structure de recherche
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Faculty of Veterinary Medicine Department of Pathology Cairo University, Égypte (pays nommé en fin d’affiliation)Université ou école supérieure
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Stem Cell Lab Giza, Égypte (pays nommé en fin d’affiliation)Structure de recherche
Department of Animal Reproduction and A.I — National Research Centre (Giza, Égypte), Al-Azhar University (Égypte) et Animal Health Research Institute, avec 5 autres affiliations. Pays d’affiliation : Égypte.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.