Management of recurrent atrial fibrillation after catheter ablation: 5-year outcomes of repeat catheter ablation vs. antiarrhythmic therapy
Rattachement africain : us. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
AIMS: Recurrence of symptomatic atrial fibrillation (AF) after catheter ablation (CA) is not uncommon. However, real-world long-term data on clinical outcomes of rhythm control strategies in patients with recurrent AF after CA remain limited. METHODS AND RESULTS: Using the TriNetX database, we identified adult patients (≥18 years) with recurrent AF after index CA. A 3-month blanking period was applied, during which no rhythm-control therapy was received. Patients were classified into two groups: repeat CA or initiation of antiarrhythmic drug (AAD) therapy. Propensity score matching (PSM) was performed to balance baseline characteristics. Hazard ratios (HR) with 95% confidence intervals (CI) were calculated. Outcomes included all-cause mortality, all-cause hospitalization, heart failure (HF) exacerbation, ischaemic stroke, and major bleeding over 5 years. Among 4056 patients with recurrent AF post-CA, 17.2% underwent repeat CA. After PSM, 697 patients in the repeat CA group (mean age 68.9 ± 9.6 years; 35.7% female) and 697 in the AAD group (mean age 68.4 ± 10.0 years; 37.6% female) were analysed. Repeat CA was associated with lower all-cause mortality (3.3% vs 8.2%; HR 0.44; 95% CI, 0.27-0.72; P < 0.01), all-cause hospitalization (42.8% vs 56.4%; HR 0.71; 95% CI, 0.61-0.82; P < 0.01) and HF exacerbation (12.5% vs 24.8%; HR 0.50; 95% CI, 0.39-0.64; P < 0.01). No differences were observed in ischaemic stroke (5.3% vs 4.7%; HR 1.22; 95% CI, 0.77-1.96; P = 0.40) or major bleeding (4.6% vs 6.2%; HR 0.82; 95% CI, 0.52-1.29; P = 0.39). CONCLUSION: Repeat CA was associated with lower mortality, hospitalization, and HF exacerbation over 5 years.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Management of recurrent atrial fibrillation after catheter ablation: 5-year outcomes of repeat catheter ablation vs. antiarrhythmic therapy
- Date Crossref
- 17/08/2026
- Éditeur
- Oxford University Press (OUP)
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
-
Beaumont Hospital pays non établi dans la noticeÉtablissement de santé
-
Cleveland Clinic Department of Internal Medicine pays non établi dans la noticeÉtablissement de santé
-
WinnMed pays non établi dans la noticeOrganisation à but non lucratif
-
Mayo Clinic in Florida Department of Cardiovascular Medicine pays non établi dans la noticeÉtablissement de santé
-
SUNY Upstate Medical University Department of Internal Medicine pays non établi dans la noticeUniversité ou école supérieure
-
The University of Texas Southwestern Medical Center Department of Cardiovascular Medicine pays non établi dans la noticeÉtablissement de santé
-
Mayo Clinic in Arizona pays non établi dans la noticeÉtablissement de santé
-
Corewell Health William Beaumont University Hospital Department of Internal Medicine/Pediatrics pays non établi dans la noticeUniversité ou école supérieure
-
Insight Hospital and Medical Center Department of Internal Medicine pays non établi dans la noticeÉtablissement de santé
Beaumont Hospital, Department of Internal Medicine — Cleveland Clinic et WinnMed, avec 6 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.