Comorbid Inflammatory Diseases in Behçet's Disease: A Multicenter Large Cohort Study
Rattachement africain : tr, ag, kh. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
OBJECTIVES: Behçet's disease (BD) is a chronic, multisystem immune-mediated vasculitis. A significant number of patients with BD have inflammatory comorbid (IC) disease that can affect the clinical course of the disease. In the current literature, there is no study which investigated IC disease in BD. It was aimed to show the prevalence and clinical spectrum of IC disease in patients with BD. METHODS: A total of 1591 patients diagnosed with BD and followed at five tertiary healthcare facilities were enrolled in the study. Patients were divided according to the presence of IC disease. Demographic characteristics, clinical manifestations, and laboratory parameters were systematically noted from medical records. The activity of the disease was evaluated by Behçet's Disease Current Activity Form (BDCAF). RESULTS: Inflammatory comorbid diseases were identified in 246 (15.3%) patients. The most common comorbidities were axial spondyloarthritis (n = 115, 7.2%), familial Mediterranean fever (FMF) (n = 38, 2.4%), and hidradenitis suppurativa (n = 37, 2.3%). Patients with IC disease had a greater use of anti-TNF treatment (p = 0.03). In the multivariate analysis, older age, and longer disease duration were found to be significantly associated with IC disease in BD (p < 0.05). CONCLUSION: BD can be associated with other inflammatory conditions. Furthermore, patients with inflammatory comorbidities were more likely to receive anti-TNF therapy, although this may partly reflect treatment indications for the comorbid conditions themselves. Therefore, clinicians should remain vigilant for inflammatory comorbidities, as their recognition may have implications for therapeutic decision-making.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Comorbid Inflammatory Diseases in Behçet's Disease: A Multicenter Large Cohort Study
- Date Crossref
- 01/08/2026
- Éditeur
- Wiley
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Sağlık Bilimleri Üniversitesi pays non établi dans la noticeUniversité ou école supérieure
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University of Health Sciences Antigua pays non établi dans la noticeUniversité ou école supérieure
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Gazi University Department of Internal Medicine pays non établi dans la noticeUniversité ou école supérieure
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Ege University Department of Internal Medicine pays non établi dans la noticeUniversité ou école supérieure
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Usak University Department of Internal Medicine pays non établi dans la noticeUniversité ou école supérieure
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Izmir University pays non établi dans la noticeUniversité ou école supérieure
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Medical Park Gaziantep Hospital pays non établi dans la noticeÉtablissement de santé
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University of Health Science Department of Internal Medicine pays non établi dans la noticeUniversité ou école supérieure
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Division of Rheumatology Medical Point Hospital Gaziantep Turkiye Department of Internal Medicine pays non établi dans la noticeÉtablissement de santé
Sağlık Bilimleri Üniversitesi, University of Health Sciences Antigua et Department of Internal Medicine — Gazi University, avec 6 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.