Supplementary Figure S1 from Glycoprotein Mucin 13 Expression as a Theranostic Target in Colorectal Cancer

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Supplementary Figure S1. A. Distribution of MUC13 mRNA expression (z-score) among Consensus Molecular Subtypes (CMS). The Kruskal-Wallis test revealed no significant differences among the groups (P=0.16). B. MUC13 expression values of 207 patients in the Integromics data set with z-score values above the cohort median (z=0.12) grouped as 'High', and with z-score values less than or equal to the median classified as ‘Low’. C. Total mutation burden (log10-transformed) compared between MUC13 High and Low groups, showing no significant difference (unpaired two-tailed Student’s t test). D. Violin plots showing differential expression levels of APC, SMAD4, and CTNNB1 between MUC13 High and Low groups. P-values were calculated using unpaired two-tailed Student’s t tests. E. Heatmap of enrichment scores for hallmark pathways differentially enriched between MUC13 High and Low groups. Rows represent hallmark pathways, and columns represent individual samples, clustered by hierarchical clustering.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.