Contextualizing functional criticality in the human cortex using neuromaps

Le résumé fourni par la source

This project investigates the spatial organization of functional criticality in the human cortex. Functional criticality is operationalized using the vertex-wise Index of Functional Criticality (vIFC), which assigns a criticality-related value to each cortical location. The study uses an existing HCP100 vIFC dataset based on resting-state fMRI data from the Human Connectome Project. The vIFC maps were internally computed by our research group. The study aims to derive a group-level cortical vIFC map and to contextualize its spatial pattern by comparing it with predefined cortical annotations from the neuromaps framework. These annotations represent different aspects of cortical organization, including macro-scale functional and structural organization as well as neurochemical and molecular features of the cortex. By comparing the spatial distribution of vIFC with these predefined annotations, the project aims to provide a more interpretable neurobiological context for functional criticality in the human cortex. Expected outcomes include a group-level cortical vIFC map, a set of spatial map-comparison results between vIFC and predefined cortical annotations, and an interpretation of which aspects of cortical organization show spatial similarity to functional criticality. The study is exploratory in its overall research aim, but the annotation selection, map-aggregation rules, and statistical workflow are specified in advance to increase transparency and reproducibility.

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