Literature review on Capadulla Doliocarpus dentatus (Aubl.) Standl: A plant native to Guyana with therapeutic potential

Résumé fourni par la source

Doliocarpus dentatus (Capadulla) is a Neotropical woody liana of the Dilleniaceae family. In Guyanese traditional medicine, it is widely used to treat arthritis, diabetes, gastrointestinal disorders, and leishmanial ulcers, as well as an aphrodisiac and general tonic. Phytochemical studies reveal a rich profile of flavonoids, tannins, phenols, lignans, and triterpenoids (including betulinic acid) that exhibit documented anti-inflammatory, antioxidant, and antimycobacterial activities with low preclinical toxicity. This narrative review synthesizes current knowledge on the taxonomy, ecology, phytochemistry, pharmacology, and metabolomics of D. dentatus. While highlighting advancements in understanding its chemodiversity, this review also identifies critical research gaps in mechanisms of action, extract standardization, and conservation. Integrating these perspectives provides a foundation for future evidence-based utilization of D. dentatus as a sustainable therapeutic Key words: Doliocarpus dentatus, Guyana, review, current knowledge, scientific databases.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.