Greenness exposure across the cancer continuum: The role of coronary heart disease
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Le résumé fourni par la source
Background: Whether residential greenness affects cancer outcomes across the cancer continuum and whether comorbid coronary heart disease (CHD) confers differential vulnerability remains an open question. We evaluated greenness-cancer associations and CHD effect modification in a pooled multicohort study. Methods: Four cohorts were pooled: two CHD patient registries and two Israeli National Health and Nutrition Surveys. Cancer and mortality data were obtained from national registries. Greenness was estimated using the Normalized Difference Vegetation Index (NDVI) within a 300 m buffer. Incident cancer cases were 1:1 matched to cancer-free controls by age, sex, cohort, and enrollment year and followed for second primary cancer incidence and mortality. Conditional logistic and Cox regression models estimated hazard ratios (HRs) per 1- standard deviation NDVI increase; CHD effect modification was tested. Results: Overall, 17,047 individuals were pooled, including 1,661 prevalent cancer cases. Over a median of 13.6 years, 2,481 incident cancer cases [age 74 (11.3) years, 27% females] were identified; 1,387 died. Prevalent cases [age 75 (10.9) years, 33% females] had 1,125 deaths over a median of 15.0 years. Greenness associations were specific to postcancer survival: NDVI-300 was not associated with first or second primary cancer incidence [HRs (95% confidence intervals) = 0.96 (0.90, 1.02) and 1.04 (0.93, 1.16), respectively]. NDVI-300 was inversely associated with postcancer mortality [HRs (95% confidence intervals) = 0.93 (0.88, 0.99) and 0.92 (0.86, 0.98) in incident and prevalent groups]. The association was consistent regardless of CHD status (all P -for-effect-modification > 0.05). Conclusions: While no association was observed for cancer incidence, residential greenness was consistently associated with lower postcancer mortality, regardless of CHD status.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Greenness exposure across the cancer continuum: The role of coronary heart disease
- Date Crossref
- 01/08/2026
- Éditeur
- Ovid Technologies (Wolters Kluwer Health)
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Tel Aviv University Department of Statistics and Operations Research pays non établi dans la noticeUniversité ou école supérieure
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Israel Ministry of Health Israel Center for Disease Control pays non établi dans la noticeOrganisme public
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University of Haifa pays non établi dans la noticeUniversité ou école supérieure
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Rabin Medical Center Department of Cardiology pays non établi dans la noticeÉtablissement de santé
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Technion – Israel Institute of Technology pays non établi dans la noticeUniversité ou école supérieure
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School of Public Health Department of Epidemiology and Preventive Medicine pays non établi dans la noticeUniversité ou école supérieure
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Technion Israel Institute of Technology Technion Center of Excellence in Exposure Science and Environmental Health pays non établi dans la noticeStructure de recherche
Department of Statistics and Operations Research — Tel Aviv University, Israel Center for Disease Control — Israel Ministry of Health et University of Haifa, avec 4 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.