Leveraging the unique properties of RNA aptamers to quantify the fraction of receptors occupied by ligands

Le résumé fourni par la source

Lord Kelvin said “When you can measure what you are speaking about … you know something about it; but when you cannot measure it … your knowledge is of a meagre and unsatisfactory kind.”1 Ligand-receptor interactions are fundamental to biology. They impact cell signaling, immune responses, and the mechanism of action of many therapeutics. Measuring ligands and receptors separately is a cornerstone of biomedical research. Quantifying the fraction of receptors occupied by their ligand has historically been more challenging.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.