Reproducibility archive for "Gradient-based experimental design for layered-tissue oximetry using a Monte Carlo uncertainty-adjusted Fisher bound"

Résumé fourni par la source

This reproducibility archive contains the analysis code, archived numerical inputs, machine-readable results, and figure-generation scripts supporting the manuscript “Gradient-based experimental design for layered-tissue oximetry using a Monte Carlo uncertainty-adjusted Fisher bound.” The archive reproduces the reported figures, tables, detector-placement optimizations, estimator-sensitivity analyses, temporal-gating and modulation-frequency studies, and tissue-property robustness analysis without rerunning the photon-transport simulations. Archived photon pools and fixed random seeds are included to support deterministic reproduction of the reported results. The study uses a differentiable layered Monte Carlo model and an uncertainty-adjusted Cramér–Rao bound to optimize continuous diffuse-optical measurement variables, including detector placement, wavelength allocation, temporal gating, and modulation frequency.