Advancing Prostate Cancer Survivorship through Transatlantic Consortium Science: The iCCaRE Initiative
Rattachement africain : us, Nigéria. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Black/African American populations, globally, bear the greatest prostate cancer burden compared with other racial/ethnic groups. Addressing prostate cancer disparities in Black men is complex, requiring a patient-centered, community-centric, and comprehensive approach. This study integrates Inclusive Cancer Care Research Equity (iCCaRE) Consortium findings and broader literature to address unmet needs in survivorship care. The iCCaRE Consortium implemented five complementary pilot studies using mixed-methods designs, including feasibility trials, qualitative research, and observational analyses across the United States and sub-Saharan Africa. Descriptive statistics, subgroup analyses, and qualitative thematic analyses were performed across these studies. Collectively, projects addressed multilevel determinants, including social, behavioral, and biological drivers of disparities. Project 1 implemented a Virtual Realty Assistant across clinical and community settings, with ongoing evaluation in pragmatic trials. Project 2 showed strong patient preference for home-based cancer care. Project 3 demonstrated trends toward improved health-related quality of life. Project 4 identified key themes influencing survivorship experiences. Project 5 identified biological mechanisms linking stress, immune modulation, and symptom burden. The iCCaRE pilot projects demonstrate the feasibility and early impact of a consortium-based, transdisciplinary approach to addressing prostate cancer disparities in Black men. These findings highlight the importance of integrating patient-centered interventions, community engagement, and biological insights to inform scalable strategies aimed at improving survivorship outcomes and advancing health equity. The iCCaRE Consortium demonstrates that a transatlantic, patient-centered, and multidisciplinary approach integrating social, clinical, and biological factors can generate scalable strategies to improve survivorship outcomes and advance equity in prostate cancer care for Black men. SIGNIFICANCE: Black men experience the highest global burden of prostate cancer, yet disparities persist due to fragmented research and limited infrastructure. The iCCaRE Consortium demonstrates how coordinated, community-engaged consortium science can accelerate equity-driven research, expand minority investigator leadership, and generate sustained funding and scholarly productivity. By integrating survivors, advocates, scientists, and clinicians across continents, iCCaRE establishes a scalable model to reduce prostate cancer disparities and advance health equity worldwide.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Advancing Prostate Cancer Survivorship through Transatlantic Consortium Science: The iCCaRE Initiative
- Date Crossref
- 01/09/2026
- Éditeur
- American Association for Cancer Research (AACR)
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Jacksonville College pays non établi dans la noticeUniversité ou école supérieure
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Mayo Clinic in Florida pays non établi dans la noticeÉtablissement de santé
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City of Hope pays non établi dans la noticeÉtablissement de santé
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Georgia College & State University pays non établi dans la noticeUniversité ou école supérieure
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Covenant University Nigéria (code pays fourni par la source)Université ou école supérieure
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Mayo Clinic in Arizona pays non établi dans la noticeÉtablissement de santé
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Global Consortium pays non établi dans la noticeInstitution
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Mayo Clinic 1 Division of Hematology/Oncology pays non établi dans la noticeÉtablissement de santé
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Beckman Research Institute pays non établi dans la noticeStructure de recherche
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Mayo Clinic 7 Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery pays non établi dans la noticeÉtablissement de santé
Jacksonville College, Mayo Clinic in Florida et City of Hope, avec 7 autres affiliations. Pays d’affiliation : Nigéria.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.